Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study
Thangavelautham Suhitharan,1 Thi Phuong Tu Pham,2 Helen Chen,2,3 Pryseley Nkouibert Assam,4 Rehena Sultana,2 Nian-Lin Reena Han,5 Ene-Choo Tan,6,7 Ban Leong Sng1,2 1Department of Women’s Anaesthesia, KK Women’s and Children’s Hospital, 2Duke-NUS Medical Sch...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2016-06-01
|
| Series: | Neuropsychiatric Disease and Treatment |
| Subjects: | |
| Online Access: | https://www.dovepress.com/investigating-analgesic-and-psychological-factors-associated-with-risk-peer-reviewed-fulltext-article-NDT |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839651705219710976 |
|---|---|
| author | Suhitharan T Pham TPT Chen H Assam PN Sultana R Han NR Tan E Sng BL |
| author_facet | Suhitharan T Pham TPT Chen H Assam PN Sultana R Han NR Tan E Sng BL |
| author_sort | Suhitharan T |
| collection | DOAJ |
| description | Thangavelautham Suhitharan,1 Thi Phuong Tu Pham,2 Helen Chen,2,3 Pryseley Nkouibert Assam,4 Rehena Sultana,2 Nian-Lin Reena Han,5 Ene-Choo Tan,6,7 Ban Leong Sng1,2 1Department of Women’s Anaesthesia, KK Women’s and Children’s Hospital, 2Duke-NUS Medical School, 3Women’s Service, Department of Psychological Medicine, KK Women’s and Children’s Hospital, 4Singapore Clinical Research Institute, 5Division of Clinical Support Services, 6Research Laboratory, KK Women’s and Children’s Hospital, 7SingHealth Paediatrics Academic Clinical Programme, Duke-NUS Medical School, Singapore Aim: The aim of this study was to investigate the role of peripartum analgesic and psychological factors that may be related to postpartum depression (PPD).Methods: This case–control study was conducted in pregnant females who delivered at KK Women’s and Children’s Hospital from November 2010 to October 2013 and had postpartum psychological assessment. Demographic, medical, and postpartum psychological status assessments, intrapartum data including method of induction of labor, mode of labor analgesia, duration of first and second stages of labor, mode of delivery, and pain intensity on hospital admission and after delivery were collected. PPD was assessed using the Edinburgh Postnatal Depression Scale and clinical assessment by the psychiatrist.Results: There were 62 cases of PPD and 417 controls after childbirth within 4–8 weeks. The odds of PPD was significantly lower (33 of 329 [10.0%]) in females who received epidural analgesia for labor compared with those who chose nonepidural analgesia (29 of 150 [19.3%]) ([odds ratio] 0.47 (0.27–0.8), P=0.0078). The multivariate analysis showed that absence of labor epidural analgesia, increasing age, family history of depression, history of depression, and previous history of PPD were independent risk factors for development of PPD.Conclusion: The absence of labor epidural analgesia remained as an independent risk factor for development of PPD when adjusted for psychiatric predictors of PPD such as history of depression or PPD and family history of depression. Keywords: epidural analgesia, childbirth, Edinburgh Postnatal Depression Scale |
| format | Article |
| id | doaj-art-a16b5e3328d348c09c77a7dda0b1fa29 |
| institution | Matheson Library |
| issn | 1178-2021 |
| language | English |
| publishDate | 2016-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Neuropsychiatric Disease and Treatment |
| spelling | doaj-art-a16b5e3328d348c09c77a7dda0b1fa292025-06-26T01:58:35ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-06-01Volume 12Issue 11333133927351Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control studySuhitharan T0Pham TPTChen HAssam PNSultana RHan NRTan ESng BL1AnesthesiologyWomen's AnaesthesiaThangavelautham Suhitharan,1 Thi Phuong Tu Pham,2 Helen Chen,2,3 Pryseley Nkouibert Assam,4 Rehena Sultana,2 Nian-Lin Reena Han,5 Ene-Choo Tan,6,7 Ban Leong Sng1,2 1Department of Women’s Anaesthesia, KK Women’s and Children’s Hospital, 2Duke-NUS Medical School, 3Women’s Service, Department of Psychological Medicine, KK Women’s and Children’s Hospital, 4Singapore Clinical Research Institute, 5Division of Clinical Support Services, 6Research Laboratory, KK Women’s and Children’s Hospital, 7SingHealth Paediatrics Academic Clinical Programme, Duke-NUS Medical School, Singapore Aim: The aim of this study was to investigate the role of peripartum analgesic and psychological factors that may be related to postpartum depression (PPD).Methods: This case–control study was conducted in pregnant females who delivered at KK Women’s and Children’s Hospital from November 2010 to October 2013 and had postpartum psychological assessment. Demographic, medical, and postpartum psychological status assessments, intrapartum data including method of induction of labor, mode of labor analgesia, duration of first and second stages of labor, mode of delivery, and pain intensity on hospital admission and after delivery were collected. PPD was assessed using the Edinburgh Postnatal Depression Scale and clinical assessment by the psychiatrist.Results: There were 62 cases of PPD and 417 controls after childbirth within 4–8 weeks. The odds of PPD was significantly lower (33 of 329 [10.0%]) in females who received epidural analgesia for labor compared with those who chose nonepidural analgesia (29 of 150 [19.3%]) ([odds ratio] 0.47 (0.27–0.8), P=0.0078). The multivariate analysis showed that absence of labor epidural analgesia, increasing age, family history of depression, history of depression, and previous history of PPD were independent risk factors for development of PPD.Conclusion: The absence of labor epidural analgesia remained as an independent risk factor for development of PPD when adjusted for psychiatric predictors of PPD such as history of depression or PPD and family history of depression. Keywords: epidural analgesia, childbirth, Edinburgh Postnatal Depression Scalehttps://www.dovepress.com/investigating-analgesic-and-psychological-factors-associated-with-risk-peer-reviewed-fulltext-article-NDTEpidural analgesiaPostpartum depressionEdinburgh Postnatal Depression Scale |
| spellingShingle | Suhitharan T Pham TPT Chen H Assam PN Sultana R Han NR Tan E Sng BL Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study Neuropsychiatric Disease and Treatment Epidural analgesia Postpartum depression Edinburgh Postnatal Depression Scale |
| title | Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study |
| title_full | Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study |
| title_fullStr | Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study |
| title_full_unstemmed | Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study |
| title_short | Investigating analgesic and psychological factors associated with risk of postpartum depression development: a case–control study |
| title_sort | investigating analgesic and psychological factors associated with risk of postpartum depression development a case amp ndash control study |
| topic | Epidural analgesia Postpartum depression Edinburgh Postnatal Depression Scale |
| url | https://www.dovepress.com/investigating-analgesic-and-psychological-factors-associated-with-risk-peer-reviewed-fulltext-article-NDT |
| work_keys_str_mv | AT suhitharant investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT phamtpt investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT chenh investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT assampn investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT sultanar investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT hannr investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT tane investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy AT sngbl investigatinganalgesicandpsychologicalfactorsassociatedwithriskofpostpartumdepressiondevelopmentacaseampndashcontrolstudy |