Benzodiazepine-conjugated pectin hydrogel beads: A controlled and targeted anticancer oral delivery system

This study was designed to improve the bioactivity of pectin (Pec) by covalently functionalizing it with benzodiazepine (Benz) via a green and efficient Mannich multicomponent reaction. The resulting Benz-functionalized pectin (Benz-Pec) was subsequently incorporated into a calcium-crosslinked hydro...

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Bibliographic Details
Main Authors: Narges Zokaei Golestan, Siamak Javanbakht, Ahmad Shaabani, Mohammad Taghi Nazeri, Fahimeh Kazeminava
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625005612
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