The Results of Preclinical Studies Assessing the Effect of Riamilovir on the Reproductive Function and Postnatal Growth of Offspring in Laboratory Animals

The Results of Preclinical Studies Assessing the Effect of Riamilovir on the Reproductive Function and Postnatal Growth of Offspring in Laboratory Animals

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The paper presents the results of extended preclinical studies demonstrating the safety using the direct-acting antiviral drug Riamilovir in immature white rats. Riamilovir did not show any toxic effects on the growth of animals, their fertility, behavior, hematological and biochemical parameters, a...

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Bibliographic Details
Main Authors: A. U. Sabitov, L. P. Larionov, M. N. Dobrinskaya, O. V. Ledyankina, A. V. Osipenko, I. E. Valamina, E. V. Philippova, I. M. Fatikhov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2023-10-01
Series:Антибиотики и Химиотерапия
Subjects:
preclinical studies
safety
immature laboratory animals
riamilovir
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/1046
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Summary:The paper presents the results of extended preclinical studies demonstrating the safety using the direct-acting antiviral drug Riamilovir in immature white rats. Riamilovir did not show any toxic effects on the growth of animals, their fertility, behavior, hematological and biochemical parameters, as well as morphology of visceral organs when used in a course. According to the results of the studies, Ramilovir can be recommended for multicenter clinical trials in adolescents and children of younger age groups.
ISSN:0235-2990

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