MEDICINAL PLANTS AND BIOLOGICALLY ACTIVE SUBSTANCES WITH ANTIFUNGAL PROPERTIES

Fungal diseases, caused by pathogenic fungi from air, soil, water, plants, and even the human body, are dangerous for humans of all age groups. Currently, commercially available antifungal agents mainly include synthetic products having numerous contraindications and severe side effects. Another pro...

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Bibliographic Details
Main Authors: ANDREY A. Mar‘In, NATALIA E. Kolomiets
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2017-12-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/69
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Summary:Fungal diseases, caused by pathogenic fungi from air, soil, water, plants, and even the human body, are dangerous for humans of all age groups. Currently, commercially available antifungal agents mainly include synthetic products having numerous contraindications and severe side effects. Another problem is a widespread resistance of fungi to antifungal agents. Therefore, the search of medicinal plants containing antifungal substances for the development of non-toxic plant drugs is rapidly ongoing. Experimental studies show the high efficiency of even minimum concentrations of biologically active substances (essential oils, saponins, flavonoids etc.) against the most common fungal pathogens (Microsporum canis, Trichophyton rubrum, Trichophyton mentagrophytes). These data indicate the possibility of using medicinal plants to prepare novel efficient antifungal agents.
ISSN:2500-0764
2542-0941