Modern algorithms for statin therapy

HMG-CoA reductase inhibitors (statins) are a key class of drugs for the treatment and prevention of atherosclerosis and its complications. This class of drugs has become firmly established in Russian and international guidelines with a high level of evidence. However, the use of these drugs in pract...

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Main Author: V. A. Susekov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2023-11-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/5594
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author V. A. Susekov
author_facet V. A. Susekov
author_sort V. A. Susekov
collection DOAJ
description HMG-CoA reductase inhibitors (statins) are a key class of drugs for the treatment and prevention of atherosclerosis and its complications. This class of drugs has become firmly established in Russian and international guidelines with a high level of evidence. However, the use of these drugs in practice is not yet optimal. A significant proportion of patients at very high cardiovascular risk, taking initial doses of statins, do not achieve target levels of low-density lipoprotein cholesterol. The article is devoted to the analysis of international and Russian guidelines for statin monotherapy optimization, including their prescription in primary prevention using cardiovascular risk reclassification, coronary calcium score, carotid Doppler ultrasound and lipoprotein(a) levels.
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language Russian
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publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-a099a7de6ba94e18b139a729bb956b8c2025-08-04T13:00:31Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202023-11-01281010.15829/1560-4071-2023-55943912Modern algorithms for statin therapyV. A. Susekov0Russian Medical Academy of Continuous Professional EducationHMG-CoA reductase inhibitors (statins) are a key class of drugs for the treatment and prevention of atherosclerosis and its complications. This class of drugs has become firmly established in Russian and international guidelines with a high level of evidence. However, the use of these drugs in practice is not yet optimal. A significant proportion of patients at very high cardiovascular risk, taking initial doses of statins, do not achieve target levels of low-density lipoprotein cholesterol. The article is devoted to the analysis of international and Russian guidelines for statin monotherapy optimization, including their prescription in primary prevention using cardiovascular risk reclassification, coronary calcium score, carotid Doppler ultrasound and lipoprotein(a) levels.https://russjcardiol.elpub.ru/jour/article/view/5594hmg-coa reductase inhibitorsstatinsatorvastatinrosuvastatinguidelinesalgorithmscoronary calciumcarotid atherosclerosislipoprotein(a)
spellingShingle V. A. Susekov
Modern algorithms for statin therapy
Российский кардиологический журнал
hmg-coa reductase inhibitors
statins
atorvastatin
rosuvastatin
guidelines
algorithms
coronary calcium
carotid atherosclerosis
lipoprotein(a)
title Modern algorithms for statin therapy
title_full Modern algorithms for statin therapy
title_fullStr Modern algorithms for statin therapy
title_full_unstemmed Modern algorithms for statin therapy
title_short Modern algorithms for statin therapy
title_sort modern algorithms for statin therapy
topic hmg-coa reductase inhibitors
statins
atorvastatin
rosuvastatin
guidelines
algorithms
coronary calcium
carotid atherosclerosis
lipoprotein(a)
url https://russjcardiol.elpub.ru/jour/article/view/5594
work_keys_str_mv AT vasusekov modernalgorithmsforstatintherapy