Targeted Isolation of ω-3 Polyunsaturated Fatty Acids from the Marine Dinoflagellate <i>Prorocentrum lima</i> Using DeepSAT and LC-MS/MS and Their High Activity in Promoting Microglial Functions

Targeted Isolation of ω-3 Polyunsaturated Fatty Acids from the Marine Dinoflagellate <i>Prorocentrum lima</i> Using DeepSAT and LC-MS/MS and Their High Activity in Promoting Microglial Functions

In this study, we integrated HSQC-based DeepSAT with UPLC-MS/MS to guide the isolation of omega-3 polyunsaturated fatty acid derivatives (PUFAs) from marine resources. Through this approach, four new (<b>1</b>–<b>4</b>) and nine known (<b>5</b>–<b>13</b&g...

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Détails bibliographiques
Auteurs principaux: Chang-Rong Lai, Meng-Xing Jiang, Dan-Mei Tian, Wei Lu, Bin Wu, Jin-Shan Tang, Yi Zou, Song-Hui Lv, Xin-Sheng Yao
Format: Article
Langue:anglais
Publié: MDPI AG 2025-07-01
Collection:Marine Drugs
Sujets:
<i>Prorocentrum lima</i>
omega-3 polyunsaturated fatty acid (ω-3 PUFA)
targeted isolation
DeepSAT
UPLC-MS/MS
microglia migration
Accès en ligne:https://www.mdpi.com/1660-3397/23/7/286
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