Biocatalysis has been used in industrial settings, especially in the pharmaceutical industry, for decades. In this review, we showcase the six most prominent enzyme classes in industrial biocatalysis: keto-reductases, ene-reductases, imine-reductases, transaminases, oxygenases, and hydrolases. For e...

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Bibliographic Details
Main Authors: Gilio, Amelia K., Abdo, Miguel A., Martinez, Carlos A., Palaia, Andrew T., Livada, Jovan
Format: Article
Language:English
Published: Académie des sciences 2025-07-01
Series:Comptes Rendus. Chimie
Subjects:
Enzyme
Biocatalysis
Hydrolase
Ketoreductase
Imine-reductase
Ene-reductase
Transaminase
Online Access:https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.408/
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Summary:Biocatalysis has been used in industrial settings, especially in the pharmaceutical industry, for decades. In this review, we showcase the six most prominent enzyme classes in industrial biocatalysis: keto-reductases, ene-reductases, imine-reductases, transaminases, oxygenases, and hydrolases. For each class, several examples are presented that highlight the substrate scope and enantioselectivity of these biotransformations from milligram to multikilogram scale.
ISSN:1878-1543

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