VARIABILITY OF THE INFLUENZA A VIRUS

Aim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel ag...

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Main Authors: I. A. Sobolev, O. G. Kurskaya, K. A. Sharshov, E. A. Prokopyeva, A. Yu. Alekseev, A. A. Gadzhiev, A. M. Shestopalov
Format: Article
Language:Russian
Published: Kamerton 2016-03-01
Series:Юг России: экология, развитие
Subjects:
Online Access:https://ecodag.elpub.ru/ugro/article/view/814
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author I. A. Sobolev
O. G. Kurskaya
K. A. Sharshov
E. A. Prokopyeva
A. Yu. Alekseev
A. A. Gadzhiev
A. M. Shestopalov
author_facet I. A. Sobolev
O. G. Kurskaya
K. A. Sharshov
E. A. Prokopyeva
A. Yu. Alekseev
A. A. Gadzhiev
A. M. Shestopalov
author_sort I. A. Sobolev
collection DOAJ
description Aim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel agencies health and reduced manpower. Features of the influenza virus genome enable the pathogen to cause seasonal epidemics each year, despite the preventive measures (vaccination) and using of specific antiviral drugs.Conclusion. Variability of the influenza virus genome is provided by antigenic drift, antigenic shift and recombination. This mechanisms of the variability of influenza virus that allow to remain a highly contagious infectious agent able to infect a large number of host species and cause significant problems as a result of epidemics and pandemics.
format Article
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institution Matheson Library
issn 1992-1098
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language Russian
publishDate 2016-03-01
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record_format Article
series Юг России: экология, развитие
spelling doaj-art-9f3696e4e385440bbd028b9ee717d43d2025-08-04T10:38:42ZrusKamertonЮг России: экология, развитие1992-10982413-09582016-03-0111117017710.18470/1992-1098-2016-1-170-177814VARIABILITY OF THE INFLUENZA A VIRUSI. A. Sobolev0O. G. Kurskaya1K. A. Sharshov2E. A. Prokopyeva3A. Yu. Alekseev4A. A. Gadzhiev5A. M. Shestopalov6Research Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineResearch Institute of Experimental and Clinical MedicineDagestan State UniversityResearch Institute of Experimental and Clinical MedicineAim. To investigate the mechanisms of variability of the influenza virus.Discussion. Influenza is one of the most significant problems facing the health care system. Human influenza causes a number of social and economic problems: mortality in high-risk groups, increasing in the load on personnel agencies health and reduced manpower. Features of the influenza virus genome enable the pathogen to cause seasonal epidemics each year, despite the preventive measures (vaccination) and using of specific antiviral drugs.Conclusion. Variability of the influenza virus genome is provided by antigenic drift, antigenic shift and recombination. This mechanisms of the variability of influenza virus that allow to remain a highly contagious infectious agent able to infect a large number of host species and cause significant problems as a result of epidemics and pandemics.https://ecodag.elpub.ru/ugro/article/view/814influenza virusvariabilityantigenic driftantigenic shifthemagglutininneuraminidaseevolution
spellingShingle I. A. Sobolev
O. G. Kurskaya
K. A. Sharshov
E. A. Prokopyeva
A. Yu. Alekseev
A. A. Gadzhiev
A. M. Shestopalov
VARIABILITY OF THE INFLUENZA A VIRUS
Юг России: экология, развитие
influenza virus
variability
antigenic drift
antigenic shift
hemagglutinin
neuraminidase
evolution
title VARIABILITY OF THE INFLUENZA A VIRUS
title_full VARIABILITY OF THE INFLUENZA A VIRUS
title_fullStr VARIABILITY OF THE INFLUENZA A VIRUS
title_full_unstemmed VARIABILITY OF THE INFLUENZA A VIRUS
title_short VARIABILITY OF THE INFLUENZA A VIRUS
title_sort variability of the influenza a virus
topic influenza virus
variability
antigenic drift
antigenic shift
hemagglutinin
neuraminidase
evolution
url https://ecodag.elpub.ru/ugro/article/view/814
work_keys_str_mv AT iasobolev variabilityoftheinfluenzaavirus
AT ogkurskaya variabilityoftheinfluenzaavirus
AT kasharshov variabilityoftheinfluenzaavirus
AT eaprokopyeva variabilityoftheinfluenzaavirus
AT ayualekseev variabilityoftheinfluenzaavirus
AT aagadzhiev variabilityoftheinfluenzaavirus
AT amshestopalov variabilityoftheinfluenzaavirus