POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION
The review of the modern data about bacteriophages and to their application to surgery is presented. Interest to bacteriophages is closely connected with an urgency of a problem of postoperative infectious complications and to resistance increase nosocomial species microbes to antibiotics. Successfu...
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| Format: | Article |
| Language: | Russian |
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2012-03-01
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| Series: | Вестник трансплантологии и искусственных органов |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/120 |
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| _version_ | 1839573997286588416 |
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| author | N.I. Gabrielyan E.M. Gorskaya O.M. Tsirulnikova |
| author_facet | N.I. Gabrielyan E.M. Gorskaya O.M. Tsirulnikova |
| author_sort | N.I. Gabrielyan |
| collection | DOAJ |
| description | The review of the modern data about bacteriophages and to their application to surgery is presented. Interest to bacteriophages is closely connected with an urgency of a problem of postoperative infectious complications and to resistance increase nosocomial species microbes to antibiotics. Successful demonstrative application of bacteriophages on experimental models for a reduction of is conditional-pathogenic microbes in biofilms, for treatment septicemia at the animals, caused resistance species P. aeruginosa, Klebsiella spp., Staphylococcus and other microbes is described. Positive results on application of bacteriophages in surgery are received at treatment of the infected wounds, peritonitis, infectious complications after liver and kidney transplantation. New mechanisms of action of bacteriophages, including their influence on transplantology immunity are resulted. Use of phages as alternatives of treatment and preventive maintenance of a superinfection at imunocomprometive patients is perspective. |
| format | Article |
| id | doaj-art-9e94b5894e6c4ceea6c1e263ede4e22f |
| institution | Matheson Library |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2012-03-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-9e94b5894e6c4ceea6c1e263ede4e22f2025-08-04T14:02:02ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912012-03-0114110611310.15825/1995-1191-2012-1-106-11363POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATIONN.I. Gabrielyan0E.M. Gorskaya1O.M. Tsirulnikova2Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe review of the modern data about bacteriophages and to their application to surgery is presented. Interest to bacteriophages is closely connected with an urgency of a problem of postoperative infectious complications and to resistance increase nosocomial species microbes to antibiotics. Successful demonstrative application of bacteriophages on experimental models for a reduction of is conditional-pathogenic microbes in biofilms, for treatment septicemia at the animals, caused resistance species P. aeruginosa, Klebsiella spp., Staphylococcus and other microbes is described. Positive results on application of bacteriophages in surgery are received at treatment of the infected wounds, peritonitis, infectious complications after liver and kidney transplantation. New mechanisms of action of bacteriophages, including their influence on transplantology immunity are resulted. Use of phages as alternatives of treatment and preventive maintenance of a superinfection at imunocomprometive patients is perspective.https://journal.transpl.ru/vtio/article/view/120banff, transplantation, allograft rejection, histological lesions, genomic markers. |
| spellingShingle | N.I. Gabrielyan E.M. Gorskaya O.M. Tsirulnikova POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION Вестник трансплантологии и искусственных органов banff, transplantation, allograft rejection, histological lesions, genomic markers. |
| title | POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION |
| title_full | POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION |
| title_fullStr | POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION |
| title_full_unstemmed | POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION |
| title_short | POSSIBILITES OF BACTERIOPHAGES APPLICATION IN SURGERY AND TRANSPLANTATION |
| title_sort | possibilites of bacteriophages application in surgery and transplantation |
| topic | banff, transplantation, allograft rejection, histological lesions, genomic markers. |
| url | https://journal.transpl.ru/vtio/article/view/120 |
| work_keys_str_mv | AT nigabrielyan possibilitesofbacteriophagesapplicationinsurgeryandtransplantation AT emgorskaya possibilitesofbacteriophagesapplicationinsurgeryandtransplantation AT omtsirulnikova possibilitesofbacteriophagesapplicationinsurgeryandtransplantation |