Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses

Designing Sandwich ELISA with Broadly Reactive Anti-Nucleocapsid Monoclonal Antibodies to Detect Bat-Borne Merbecoviruses

At least three betacoronaviruses have spilled over from bats to humans and caused severe diseases, highlighting the threat of zoonotic transmission. Thus, it is important to enhance surveillance capabilities by developing tools capable of detecting a broad spectrum of bat-borne betacoronaviruses. Th...

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Bibliographic Details
Main Authors: Kong Yen Liew, Yaju Wang, Sneha Sree Mullapudi, Dinah binte Aziz, Wenjie Fan, Min Luo, Paul Anantharajah Tambyah, Yee-Joo Tan
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Viruses
Subjects:
betacoronavirus
nucleocapsid protein
monoclonal antibody
sandwich ELISA
bat-borne viruses
zoonotic surveillance
Online Access:https://www.mdpi.com/1999-4915/17/7/886
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