Neuroendocrine Tumours: a Literature Review
Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from th...
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Bashkir State Medical University
2021-05-01
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Series: | Креативная хирургия и онкология |
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Online Access: | https://www.surgonco.ru/jour/article/view/588 |
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author | K. V. Menshikov A. V. Sultanbaev Sh. I. Musin I. A. Menshikova A. F. Nasretdinov N. I. Sultanbaeva I. R. Shaykhutdinov |
author_facet | K. V. Menshikov A. V. Sultanbaev Sh. I. Musin I. A. Menshikova A. F. Nasretdinov N. I. Sultanbaeva I. R. Shaykhutdinov |
author_sort | K. V. Menshikov |
collection | DOAJ |
description | Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease. |
format | Article |
id | doaj-art-9d96be37f5e4432488cd8ab75a7b2ba0 |
institution | Matheson Library |
issn | 2076-3093 2307-0501 |
language | English |
publishDate | 2021-05-01 |
publisher | Bashkir State Medical University |
record_format | Article |
series | Креативная хирургия и онкология |
spelling | doaj-art-9d96be37f5e4432488cd8ab75a7b2ba02025-08-03T19:48:54ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012021-05-0111217418210.24060/2076-3093-2021-11-2-174-182433Neuroendocrine Tumours: a Literature ReviewK. V. Menshikov0A. V. Sultanbaev1Sh. I. Musin2I. A. Menshikova3A. F. Nasretdinov4N. I. Sultanbaeva5I. R. Shaykhutdinov6Republican Clinical Oncological Dispensary; Bashkir State Medical UniversityRepublican Clinical Oncological DispensaryRepublican Clinical Oncological DispensaryBashkir State Medical UniversityRepublican Clinical Oncological DispensaryRepublican Clinical Oncological DispensaryBashkir State Medical UniversityNeuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease.https://www.surgonco.ru/jour/article/view/588neuroendocrine tumourcarcinoidcarcinoid syndromesomatostatin analoguestumour classification |
spellingShingle | K. V. Menshikov A. V. Sultanbaev Sh. I. Musin I. A. Menshikova A. F. Nasretdinov N. I. Sultanbaeva I. R. Shaykhutdinov Neuroendocrine Tumours: a Literature Review Креативная хирургия и онкология neuroendocrine tumour carcinoid carcinoid syndrome somatostatin analogues tumour classification |
title | Neuroendocrine Tumours: a Literature Review |
title_full | Neuroendocrine Tumours: a Literature Review |
title_fullStr | Neuroendocrine Tumours: a Literature Review |
title_full_unstemmed | Neuroendocrine Tumours: a Literature Review |
title_short | Neuroendocrine Tumours: a Literature Review |
title_sort | neuroendocrine tumours a literature review |
topic | neuroendocrine tumour carcinoid carcinoid syndrome somatostatin analogues tumour classification |
url | https://www.surgonco.ru/jour/article/view/588 |
work_keys_str_mv | AT kvmenshikov neuroendocrinetumoursaliteraturereview AT avsultanbaev neuroendocrinetumoursaliteraturereview AT shimusin neuroendocrinetumoursaliteraturereview AT iamenshikova neuroendocrinetumoursaliteraturereview AT afnasretdinov neuroendocrinetumoursaliteraturereview AT nisultanbaeva neuroendocrinetumoursaliteraturereview AT irshaykhutdinov neuroendocrinetumoursaliteraturereview |