Neuroendocrine Tumours: a Literature Review

Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from th...

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Main Authors: K. V. Menshikov, A. V. Sultanbaev, Sh. I. Musin, I. A. Menshikova, A. F. Nasretdinov, N. I. Sultanbaeva, I. R. Shaykhutdinov
Format: Article
Language:English
Published: Bashkir State Medical University 2021-05-01
Series:Креативная хирургия и онкология
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Online Access:https://www.surgonco.ru/jour/article/view/588
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author K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
author_facet K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
author_sort K. V. Menshikov
collection DOAJ
description Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease.
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publishDate 2021-05-01
publisher Bashkir State Medical University
record_format Article
series Креативная хирургия и онкология
spelling doaj-art-9d96be37f5e4432488cd8ab75a7b2ba02025-08-03T19:48:54ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012021-05-0111217418210.24060/2076-3093-2021-11-2-174-182433Neuroendocrine Tumours: a Literature ReviewK. V. Menshikov0A. V. Sultanbaev1Sh. I. Musin2I. A. Menshikova3A. F. Nasretdinov4N. I. Sultanbaeva5I. R. Shaykhutdinov6Republican Clinical Oncological Dispensary; Bashkir State Medical UniversityRepublican Clinical Oncological DispensaryRepublican Clinical Oncological DispensaryBashkir State Medical UniversityRepublican Clinical Oncological DispensaryRepublican Clinical Oncological DispensaryBashkir State Medical UniversityNeuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease.https://www.surgonco.ru/jour/article/view/588neuroendocrine tumourcarcinoidcarcinoid syndromesomatostatin analoguestumour classification
spellingShingle K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
Neuroendocrine Tumours: a Literature Review
Креативная хирургия и онкология
neuroendocrine tumour
carcinoid
carcinoid syndrome
somatostatin analogues
tumour classification
title Neuroendocrine Tumours: a Literature Review
title_full Neuroendocrine Tumours: a Literature Review
title_fullStr Neuroendocrine Tumours: a Literature Review
title_full_unstemmed Neuroendocrine Tumours: a Literature Review
title_short Neuroendocrine Tumours: a Literature Review
title_sort neuroendocrine tumours a literature review
topic neuroendocrine tumour
carcinoid
carcinoid syndrome
somatostatin analogues
tumour classification
url https://www.surgonco.ru/jour/article/view/588
work_keys_str_mv AT kvmenshikov neuroendocrinetumoursaliteraturereview
AT avsultanbaev neuroendocrinetumoursaliteraturereview
AT shimusin neuroendocrinetumoursaliteraturereview
AT iamenshikova neuroendocrinetumoursaliteraturereview
AT afnasretdinov neuroendocrinetumoursaliteraturereview
AT nisultanbaeva neuroendocrinetumoursaliteraturereview
AT irshaykhutdinov neuroendocrinetumoursaliteraturereview