Possible role of Lactobacillus reuteri for eradication of Helicobacter pylori in adults in real clinical practice

The high prevalence of Helicobacter pylori infection and the low efficiency of its eradication in real clinical practice motivate to search for ways to optimize the used treatment regimens. The article highlights data on prevalence, transmission routes, modern methods of diagnosis and treatment of H...

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Bibliographic Details
Main Authors: I. B. Khlynov, R. I. Akimenko, E. I. Voronova, E. V. Garanina, I. A. Gurikova, M. E. Loseva, O. G. Marchenko, C. V. Odinets, P. Yu. Pinigina, O. A. Ryabinina, E. B. Freze
Format: Article
Language:Russian
Published: Open Systems Publication 2021-06-01
Series:Лечащий Врач
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Online Access:https://journal.lvrach.ru/jour/article/view/80
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Summary:The high prevalence of Helicobacter pylori infection and the low efficiency of its eradication in real clinical practice motivate to search for ways to optimize the used treatment regimens. The article highlights data on prevalence, transmission routes, modern methods of diagnosis and treatment of Helicobacter pylori associated diseases. The experience of real clinical practice based on the data of the territorial register of eradication therapy in Yekaterinburg in 2018-2019 is given. When analyzing the ambulatory charts of 437 patients, the efficacy and safety of standard triple therapy with bismuth was studied compared to the combination of standard triple therapy with bismuth and a metabiotic based on Lactobacillus reuteri DSMZ17648. Additional administration of metabiotics increased the eradication efficiency by 5.9%, and the frequency of adverse events decreased by 18.1%.
ISSN:1560-5175
2687-1181