A CNTNAP1 Missense Variant Associated With Laryngeal Paralysis and Polyneuropathy in Young Great Dane Dogs

A CNTNAP1 Missense Variant Associated With Laryngeal Paralysis and Polyneuropathy in Young Great Dane Dogs

ABSTRACT Background Major genetic risk loci and causative mutations classified as LPN1 (Leonberger polyneuropathy type 1), LPN2 (Leonberger polyneuropathy type 2), and LPPN3 (Laryngeal paralysis polyneuropathy type 3) have been identified in Leonberger and Saint Bernard dogs with laryngeal paralysis...

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Bibliographic Details
Main Authors: G. Diane Shelton, Missy C. Carpentier, Y. Michael Kimura, Ling T. Guo, Katie M. Minor
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Veterinary Internal Medicine
Subjects:
canine
genetic disease
lower motor neuron disease
peripheral nerve
weakness
Online Access:https://doi.org/10.1111/jvim.70185
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