Results of Accelerated Local Cross-Linking in Keratoconus
Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods. Thirty-four patients (42 eyes) were included in the study: 19 people (24 eyes) with stage II keratoconus, 15 people (18 eyes) with stage III Ams...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Ophthalmology Publishing Group
2023-10-01
|
| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/2168 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839571045329141760 |
|---|---|
| author | H. Khraistin G. A. Osipyan S. I. Anisimov A. K. Dzamikhova M. Jourieh |
| author_facet | H. Khraistin G. A. Osipyan S. I. Anisimov A. K. Dzamikhova M. Jourieh |
| author_sort | H. Khraistin |
| collection | DOAJ |
| description | Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods. Thirty-four patients (42 eyes) were included in the study: 19 people (24 eyes) with stage II keratoconus, 15 people (18 eyes) with stage III Amsler keratoconus. All patients were examined using the following methods: visometry, refractokeratometry, keratotopography, optical coherence tomography of anterior segment, endothelial cell density calculation before and after surgical treatment in 6 months, 1, 2 and 3 years. Results. Significant increase of uncorrected (UDVA) and corrected (CDVA) distance visual acuity was registered 6 months after operation in KC of the II and III stages. In KC stage II, the NCOZ and EOC were greater, from 0.39 ± 0.14 to 0.61 ± 0.18 by 0.22 ± 0.04 (p < 0.05) and from 0.60 ± 0.15 to 0.77 ± 0.12 by 0.17 ± 0.03 (p < 0.05), respectively, in stage III. — from 0.12 ± 0.03 to 0.23 ± 0.07 by 0.12 ± 0.04 (p < 0.05) and from 0.45 ± 0.10 to 0.53 ± 0.12 by 0.10 ± 0.02 (p < 0.05), due to decreased refractive indices in the central 3.0 mm zone. Refractive indexes of the central corneal zone, UVA and CVA in all patients after one, two and three years, as well as data of minimal corneal thickness and endothelial cell density did not change statistically significantly during the entire observation period. |
| format | Article |
| id | doaj-art-9d6948eecd7b4cdfac3faa54d9675ef3 |
| institution | Matheson Library |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| publishDate | 2023-10-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj-art-9d6948eecd7b4cdfac3faa54d9675ef32025-08-04T14:32:25ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452023-10-0120343744310.18008/1816-5095-2023-3-437-4431053Results of Accelerated Local Cross-Linking in KeratoconusH. Khraistin0G. A. Osipyan1S. I. Anisimov2A. K. Dzamikhova3M. Jourieh4M.M. Krasnov Scientific Research Institute of Eye Diseases; Center Vision RecoveryM.M. Krasnov Scientific Research Institute of Eye Diseases; Center Vision RecoveryEvdokimov Moscow State University of Medicine and DentistryM.M. Krasnov Scientific Research Institute of Eye DiseasesI.M. Sechenov First Moscow State Medical University (Sechenov University)Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods. Thirty-four patients (42 eyes) were included in the study: 19 people (24 eyes) with stage II keratoconus, 15 people (18 eyes) with stage III Amsler keratoconus. All patients were examined using the following methods: visometry, refractokeratometry, keratotopography, optical coherence tomography of anterior segment, endothelial cell density calculation before and after surgical treatment in 6 months, 1, 2 and 3 years. Results. Significant increase of uncorrected (UDVA) and corrected (CDVA) distance visual acuity was registered 6 months after operation in KC of the II and III stages. In KC stage II, the NCOZ and EOC were greater, from 0.39 ± 0.14 to 0.61 ± 0.18 by 0.22 ± 0.04 (p < 0.05) and from 0.60 ± 0.15 to 0.77 ± 0.12 by 0.17 ± 0.03 (p < 0.05), respectively, in stage III. — from 0.12 ± 0.03 to 0.23 ± 0.07 by 0.12 ± 0.04 (p < 0.05) and from 0.45 ± 0.10 to 0.53 ± 0.12 by 0.10 ± 0.02 (p < 0.05), due to decreased refractive indices in the central 3.0 mm zone. Refractive indexes of the central corneal zone, UVA and CVA in all patients after one, two and three years, as well as data of minimal corneal thickness and endothelial cell density did not change statistically significantly during the entire observation period.https://www.ophthalmojournal.com/opht/article/view/2168corneacorneal collagen cross-linkingkeratoconuskeratectasiaaccelerated local cross-linking |
| spellingShingle | H. Khraistin G. A. Osipyan S. I. Anisimov A. K. Dzamikhova M. Jourieh Results of Accelerated Local Cross-Linking in Keratoconus Oftalʹmologiâ cornea corneal collagen cross-linking keratoconus keratectasia accelerated local cross-linking |
| title | Results of Accelerated Local Cross-Linking in Keratoconus |
| title_full | Results of Accelerated Local Cross-Linking in Keratoconus |
| title_fullStr | Results of Accelerated Local Cross-Linking in Keratoconus |
| title_full_unstemmed | Results of Accelerated Local Cross-Linking in Keratoconus |
| title_short | Results of Accelerated Local Cross-Linking in Keratoconus |
| title_sort | results of accelerated local cross linking in keratoconus |
| topic | cornea corneal collagen cross-linking keratoconus keratectasia accelerated local cross-linking |
| url | https://www.ophthalmojournal.com/opht/article/view/2168 |
| work_keys_str_mv | AT hkhraistin resultsofacceleratedlocalcrosslinkinginkeratoconus AT gaosipyan resultsofacceleratedlocalcrosslinkinginkeratoconus AT sianisimov resultsofacceleratedlocalcrosslinkinginkeratoconus AT akdzamikhova resultsofacceleratedlocalcrosslinkinginkeratoconus AT mjourieh resultsofacceleratedlocalcrosslinkinginkeratoconus |