Low-density lipoprotein receptor–related protein 1 mediates α-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson’s disease
α-Synuclein accumulation and transmission are vital to the pathogenesis of Parkinson’s disease, although the mechanisms underlying misfolded α-synuclein accumulation and propagation have not been conclusively determined. The expression of low-density lipoprotein receptor–related protein 1, which is...
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Main Authors: | Hanjiang Luo, Caixia Peng, Chengli Wu, Chengwei Liu, Qinghua Li, Shun Yu, Jia Liu, Min Chen |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2026-04-01
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Series: | Neural Regeneration Research |
Subjects: | |
Online Access: | https://journals.lww.com/10.4103/NRR.NRR-D-23-01965 |
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