Ponatinib/blinatumomab for relapsed Philadelphia chromosome-positive leukemia as a bridge to allogeneic transplantation

Ponatinib/blinatumomab for relapsed Philadelphia chromosome-positive leukemia as a bridge to allogeneic transplantation

We report three cases of ponatinib/blinatumomab (Pona/BLIN) combination therapy as a bridge to allogeneic hematopoietic cell transplantation (allo-HCT) in patients with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (r/r-Ph + ALL) or lymphoid chronic myeloid leukem...

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Main Authors: Yasutaka Sadaga, Daisuke Watanabe, Yuho Najima, Daichi Sadato, Chizuko Hirama, Kana Kato, Kaori Kondo, Chika Kato, Satoshi Sakai, Yasuhiro Kambara, Masashi Shimabukuro, Atsushi Jinguji, Naoki Shingai, Kyoko Haraguchi, Takashi Toya, Hiroaki Shimizu, Takeshi Kobayashi, Yoshiki Okuyama, Yuka Harada, Daisuke Mizuchi, Noriko Doki
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hematology
Subjects:
Ponatinib
blinatumomab
Philadelphia chromosome positive acute lymphoblastic leukemia
chronic myeloid leukemia
allogeneic hematopoietic stem cell transplantation
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2025.2539550
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