The development of functional opsonophagocytic assays to evaluate antibody responses to Klebsiella pneumoniae capsular antigens

ABSTRACT Klebsiella pneumoniae is one of the leading causes of nosocomial infections in low- and middle-income countries (LMICs), with a high mortality rate among the immunocompromised. With increasing antibiotic resistance, there is an urgent need for preventive measures such as vaccines, but none...

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Main Authors: Robert Lawrence, Emma Bownes, Marina Johnson, Heather Fox, Drew Huff, Ivan Olave, Anup Datta, David Goldblatt, Nathalie Karaky
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00176-25
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