Dermatologic toxicity of high doses of tiothepa in children. Case report
Hematopoietic stem cell transplantation (HSCT) is a treatment modality for a number of severe malignant and non-neoplastic diseases. Autologous hematopoietic stem cell transplantation (auto-HSCT) improves outcomes in patients with solid and hematological malignancies. Skin lesions at the auto-HSCT s...
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| Format: | Article |
| Language: | Russian |
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Union of pediatricians of Russia
2023-05-01
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| Series: | Педиатрическая фармакология |
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| Online Access: | https://www.pedpharma.ru/jour/article/view/2284 |
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| author | Teimur Z. Aliev Tatiana I. Potemkina Tatiana S. Belysheva Timur T. Valiev Karina A. Sergeenko Irina A. Kostareva Lana M. Kudaeva Elena B. Machneva Tatiana L. Ushakova Vladimir G. Polyakov Kirill I. Kirgizov Svetlana R. Varfolomeeva |
| author_facet | Teimur Z. Aliev Tatiana I. Potemkina Tatiana S. Belysheva Timur T. Valiev Karina A. Sergeenko Irina A. Kostareva Lana M. Kudaeva Elena B. Machneva Tatiana L. Ushakova Vladimir G. Polyakov Kirill I. Kirgizov Svetlana R. Varfolomeeva |
| author_sort | Teimur Z. Aliev |
| collection | DOAJ |
| description | Hematopoietic stem cell transplantation (HSCT) is a treatment modality for a number of severe malignant and non-neoplastic diseases. Autologous hematopoietic stem cell transplantation (auto-HSCT) improves outcomes in patients with solid and hematological malignancies. Skin lesions at the auto-HSCT stage are quite common and represent an important diagnostic and therapeutic problem. The most significant causes of skin lesions in auto-HSCT are drug toxicity, infectious and viral lesions. Each of the complications can manifest itself to varying degrees as well as combine with others, having a significant negative on the patient’s condition, posing a threat to the patient’s life in severe cases. |
| format | Article |
| id | doaj-art-9c4c3880b9d04b64a143c4e3b25d3614 |
| institution | Matheson Library |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2023-05-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-9c4c3880b9d04b64a143c4e3b25d36142025-08-03T19:21:30ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892023-05-0120210.15690/pf.v20i2.25431970Dermatologic toxicity of high doses of tiothepa in children. Case reportTeimur Z. Aliev0Tatiana I. Potemkina1Tatiana S. Belysheva2Timur T. Valiev3Karina A. Sergeenko4Irina A. Kostareva5Lana M. Kudaeva6Elena B. Machneva7Tatiana L. Ushakova8Vladimir G. Polyakov9Kirill I. Kirgizov10Svetlana R. Varfolomeeva11N.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyA.I. Yevdokimov Moscow State University of Medicine and DentistryN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and Hematology; Russian Children’s Clinical Hospital of Pirogov Russian National Research Medical UniversityN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and Hematology; Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Public Health of the Russian FederationN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and Hematology; Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuous Professional Education” of the Ministry of Public Health of the Russian Federation; Pirogov Russian National Research Medical UniversityN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyN.N. Blokhin National Medical Research Center of Oncology, L.A. Durnov Research Institute of Pediatric Oncology and HematologyHematopoietic stem cell transplantation (HSCT) is a treatment modality for a number of severe malignant and non-neoplastic diseases. Autologous hematopoietic stem cell transplantation (auto-HSCT) improves outcomes in patients with solid and hematological malignancies. Skin lesions at the auto-HSCT stage are quite common and represent an important diagnostic and therapeutic problem. The most significant causes of skin lesions in auto-HSCT are drug toxicity, infectious and viral lesions. Each of the complications can manifest itself to varying degrees as well as combine with others, having a significant negative on the patient’s condition, posing a threat to the patient’s life in severe cases.https://www.pedpharma.ru/jour/article/view/2284autologous hematopoietic stem cell transplantationdermatologic toxicityskintiothepahigh-dose chemotherapy |
| spellingShingle | Teimur Z. Aliev Tatiana I. Potemkina Tatiana S. Belysheva Timur T. Valiev Karina A. Sergeenko Irina A. Kostareva Lana M. Kudaeva Elena B. Machneva Tatiana L. Ushakova Vladimir G. Polyakov Kirill I. Kirgizov Svetlana R. Varfolomeeva Dermatologic toxicity of high doses of tiothepa in children. Case report Педиатрическая фармакология autologous hematopoietic stem cell transplantation dermatologic toxicity skin tiothepa high-dose chemotherapy |
| title | Dermatologic toxicity of high doses of tiothepa in children. Case report |
| title_full | Dermatologic toxicity of high doses of tiothepa in children. Case report |
| title_fullStr | Dermatologic toxicity of high doses of tiothepa in children. Case report |
| title_full_unstemmed | Dermatologic toxicity of high doses of tiothepa in children. Case report |
| title_short | Dermatologic toxicity of high doses of tiothepa in children. Case report |
| title_sort | dermatologic toxicity of high doses of tiothepa in children case report |
| topic | autologous hematopoietic stem cell transplantation dermatologic toxicity skin tiothepa high-dose chemotherapy |
| url | https://www.pedpharma.ru/jour/article/view/2284 |
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