Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension
According to modern views, immuno-inflammatory activation plays an important role in atrial fibrillation (AF) pathogenesis. In 97patients with arterial hypertension (AH), paroxysm and non-paroxysm levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and fibrinogen were measur...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2007-06-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2091 |
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| author | O. A. Tarasova |
| author_facet | O. A. Tarasova |
| author_sort | O. A. Tarasova |
| collection | DOAJ |
| description | According to modern views, immuno-inflammatory activation plays an important role in atrial fibrillation (AF) pathogenesis. In 97patients with arterial hypertension (AH), paroxysm and non-paroxysm levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and fibrinogen were measured in 97 patients with permanent, persisting recurrent atrial fibrillation (AF). During AF paroxysm, TNF-alpha levels were significantly increased (p = 0,0001), in contrast with relatively stable CRP and fibrinogen levels (p > 0,05). CRP inversely correlated with AF severity (p = 0,0001). TNF-alpha levels were inversely associated with high-density lipoprotein cholesterol concentration in AF-free hypertensives, AH and permanent AF individuals, and persistent recurrent AF patients during the paroxysm. AF paroxysms were linked to increased TNF-alpha concentration. The correlation between main cardiovascular risk factors and inflammatory markers was observed. |
| format | Article |
| id | doaj-art-9c3e3a9e7dcc4b0b9ed01860e89da9f5 |
| institution | Matheson Library |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| publishDate | 2007-06-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj-art-9c3e3a9e7dcc4b0b9ed01860e89da9f52025-08-04T13:00:01Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-06-010318221844Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertensionO. A. Tarasova0Пермская государственная медицинская академия им. Е.А. ВагнераAccording to modern views, immuno-inflammatory activation plays an important role in atrial fibrillation (AF) pathogenesis. In 97patients with arterial hypertension (AH), paroxysm and non-paroxysm levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha), and fibrinogen were measured in 97 patients with permanent, persisting recurrent atrial fibrillation (AF). During AF paroxysm, TNF-alpha levels were significantly increased (p = 0,0001), in contrast with relatively stable CRP and fibrinogen levels (p > 0,05). CRP inversely correlated with AF severity (p = 0,0001). TNF-alpha levels were inversely associated with high-density lipoprotein cholesterol concentration in AF-free hypertensives, AH and permanent AF individuals, and persistent recurrent AF patients during the paroxysm. AF paroxysms were linked to increased TNF-alpha concentration. The correlation between main cardiovascular risk factors and inflammatory markers was observed.https://russjcardiol.elpub.ru/jour/article/view/2091atrial fibrillationtumor necrosis factor–alphacjreactive proteinfibrinogenrisk factors |
| spellingShingle | O. A. Tarasova Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension Российский кардиологический журнал atrial fibrillation tumor necrosis factor–alpha cjreactive protein fibrinogen risk factors |
| title | Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| title_full | Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| title_fullStr | Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| title_full_unstemmed | Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| title_short | Inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| title_sort | inflammatory markers and their association with main cardiovascular risk factors in patients with atrial fibrillation and arterial hypertension |
| topic | atrial fibrillation tumor necrosis factor–alpha cjreactive protein fibrinogen risk factors |
| url | https://russjcardiol.elpub.ru/jour/article/view/2091 |
| work_keys_str_mv | AT oatarasova inflammatorymarkersandtheirassociationwithmaincardiovascularriskfactorsinpatientswithatrialfibrillationandarterialhypertension |