Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years

Aim. To establish associations between the depression level as an independent cardiovascular risk factor and cognitive impairment (patterns of memory, attention and thinking) in people aged 25-44 years.Material and methods. In 2013-2016, a random representative sample of people aged 25-44 years was...

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Main Authors: V. V. Gafarov, A. V. Sukhanov, E. A. Gromova, I. V. Gagulin, A. V. Gafarova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2024-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/3930
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author V. V. Gafarov
A. V. Sukhanov
E. A. Gromova
I. V. Gagulin
A. V. Gafarova
author_facet V. V. Gafarov
A. V. Sukhanov
E. A. Gromova
I. V. Gagulin
A. V. Gafarova
author_sort V. V. Gafarov
collection DOAJ
description Aim. To establish associations between the depression level as an independent cardiovascular risk factor and cognitive impairment (patterns of memory, attention and thinking) in people aged 25-44 years.Material and methods. In 2013-2016, a random representative sample of people aged 25-44 years was studied in one of the Novosibirsk districts. A total of 463 men (mean age 35,94±5,96 years) and 546 women (mean age 36,17±5,99 years) were examined. Standardized tests were used to assess cognitive function. Depression level was assessed according to the MOPSY (MONICA-psychosocial) World Health Organization program criteria.Results. In the surveyed random representative sample of people aged 25-44 years, the prevalence of higher education was the highest (60,5%). The depression prevalence in women was higher than in men: high depression level — 15,84 and 8,64%; the mean depression level was 25,71 and 21,3%, respectively. Univariate analysis showed that the attention stability according to the dot cancellation test at a moderate and high depression level was reduced only in men with higher education, compared with those without depression (p=0,018). In persons of both sexes with secondary professional education in a random representative sample of persons aged 25-44 years, associations between depression and memory pattern disturbances were identified. In the resulting multivariate model, men in a random representative sample of persons aged 25-44 years without depression did not have any cognitive impairment in patterns of memory, attention and thinking.Conclusion. An association has been established between the depression and cognitive impairment (patterns of memory, attention and thinking) in people aged 25-44 years.
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spelling doaj-art-9be14a22f3c84c6789e1f6b45a3e02e82025-08-04T12:50:32Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252024-06-0123510.15829/1728-8800-2024-39302974Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 yearsV. V. Gafarov0A. V. Sukhanov1E. A. Gromova2I. V. Gagulin3A. V. Gafarova4Research Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics; Interdepartmental Laboratory for Epidemiology of Cardiovascular DiseasesResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics; Interdepartmental Laboratory for Epidemiology of Cardiovascular DiseasesResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics; Interdepartmental Laboratory for Epidemiology of Cardiovascular DiseasesResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and Genetics; Interdepartmental Laboratory for Epidemiology of Cardiovascular DiseasesAim. To establish associations between the depression level as an independent cardiovascular risk factor and cognitive impairment (patterns of memory, attention and thinking) in people aged 25-44 years.Material and methods. In 2013-2016, a random representative sample of people aged 25-44 years was studied in one of the Novosibirsk districts. A total of 463 men (mean age 35,94±5,96 years) and 546 women (mean age 36,17±5,99 years) were examined. Standardized tests were used to assess cognitive function. Depression level was assessed according to the MOPSY (MONICA-psychosocial) World Health Organization program criteria.Results. In the surveyed random representative sample of people aged 25-44 years, the prevalence of higher education was the highest (60,5%). The depression prevalence in women was higher than in men: high depression level — 15,84 and 8,64%; the mean depression level was 25,71 and 21,3%, respectively. Univariate analysis showed that the attention stability according to the dot cancellation test at a moderate and high depression level was reduced only in men with higher education, compared with those without depression (p=0,018). In persons of both sexes with secondary professional education in a random representative sample of persons aged 25-44 years, associations between depression and memory pattern disturbances were identified. In the resulting multivariate model, men in a random representative sample of persons aged 25-44 years without depression did not have any cognitive impairment in patterns of memory, attention and thinking.Conclusion. An association has been established between the depression and cognitive impairment (patterns of memory, attention and thinking) in people aged 25-44 years.https://cardiovascular.elpub.ru/jour/article/view/3930cognitive functionscognitive impairmentdepressionindependent cardiovascular risk factorpatternmemoryattentionthinkingpersons 25-44 years old
spellingShingle V. V. Gafarov
A. V. Sukhanov
E. A. Gromova
I. V. Gagulin
A. V. Gafarova
Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
Кардиоваскулярная терапия и профилактика
cognitive functions
cognitive impairment
depression
independent cardiovascular risk factor
pattern
memory
attention
thinking
persons 25-44 years old
title Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
title_full Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
title_fullStr Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
title_full_unstemmed Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
title_short Depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25-44 years
title_sort depression as an independent risk factor for cardiovascular diseases and cognitive impairment in people aged 25 44 years
topic cognitive functions
cognitive impairment
depression
independent cardiovascular risk factor
pattern
memory
attention
thinking
persons 25-44 years old
url https://cardiovascular.elpub.ru/jour/article/view/3930
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AT eagromova depressionasanindependentriskfactorforcardiovasculardiseasesandcognitiveimpairmentinpeopleaged2544years
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