Biomaterial-driven regenerative drug delivery: a vicennial bibliometric landscape

IntroductionBiomaterials are increasingly central to innovations in drug delivery and regenerative medicine, driving new therapeutic strategies for chronic diseases and tissue repair. Despite rapid growth, a comprehensive, data-driven overview of this evolving interdisciplinary landscape has been la...

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Bibliographic Details
Main Authors: Xin Shen, Haobin Deng, Jing Lin, Jianhua Wang, Yilun Liu, Shikun Mo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1593985/full
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Summary:IntroductionBiomaterials are increasingly central to innovations in drug delivery and regenerative medicine, driving new therapeutic strategies for chronic diseases and tissue repair. Despite rapid growth, a comprehensive, data-driven overview of this evolving interdisciplinary landscape has been lacking.MethodsHere, we present a bibliometric analysis of articles and reviews published in the Science Citation Index Expanded (Web of Science Core Collection) from January 2005 to December 2024.Results and discussionThe findings present a bibliometric visualization that highlights key trends in publication volume, geographical distribution of research, leading institutions, top journals, research categories, and emerging keywords. Cross-disciplinary integration of biomaterials, regenerative medicine, and drug delivery is accelerating advances in stem cell-based therapies, tissue engineering, and precision drug delivery platforms. Promising frontiers include personalized medicine, organoids, organ-on-chip technologies, and digital modelling of cellular systems. However, significant challenges remain in scalability, safety, and regulatory translation. This work provides a comprehensive reference for navigating current trends and identifying future opportunities in biomaterial-driven regenerative drug delivery.
ISSN:2296-858X