Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model
ABSTRACT Purpose: To evaluate the effectiveness of a new format of prophylactic mesh, with a new method of placement. Methods: Rabbits were randomly distributed into four groups: control rabbits without laparotomy group; sutured rabbits (SR); light-weight mesh rabbits (LWMR); and heavy-weight mesh...
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| Language: | English |
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Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2025-07-01
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| Series: | Acta Cirúrgica Brasileira |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100231&lng=en&tlng=en |
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| author | Thiago de Almeida Furtado Álvaro Cota Carvalho Marcelo Lopes Furtado Luiz Ronaldo Alberti Diego Paim de Carvalho Garcia |
| author_facet | Thiago de Almeida Furtado Álvaro Cota Carvalho Marcelo Lopes Furtado Luiz Ronaldo Alberti Diego Paim de Carvalho Garcia |
| author_sort | Thiago de Almeida Furtado |
| collection | DOAJ |
| description | ABSTRACT Purpose: To evaluate the effectiveness of a new format of prophylactic mesh, with a new method of placement. Methods: Rabbits were randomly distributed into four groups: control rabbits without laparotomy group; sutured rabbits (SR); light-weight mesh rabbits (LWMR); and heavy-weight mesh rabbits (HWMR). The meshes were cut to a size of 10 cm in length by 1 cm in width. A longitudinal, median abdominal incision, 11 cm in length, was performed, followed by an incision over the linea alba, encompassing the entire thickness of the abdominal wall. On the 91st postoperative day, the animals were killed for linea alba scar evaluation. Results: There was a significant difference among the evaluated groups concerning elongation, maximum load, and elasticity modulus. HWMR and LWMR were statistically different from controls regarding elongation. As for the elasticity modulus, SR presented a higher mean when compared to the others. Microscopic visual analysis showed greater fibrotic scarring with a larger amount of implanted material in HWMR. Conclusion: The reinforcement of scars with polypropylene mesh does not increase tensile strength when compared to the use of sutures. Mesh implantation results in scar remodeling with greater fibrosis, leading to increased elongation. However, midline reinforcement using only sutures has greater elasticity than the groups reinforced with mesh. |
| format | Article |
| id | doaj-art-9a3d4c22c4744fc9a66c2d46d20ccc9f |
| institution | Matheson Library |
| issn | 1678-2674 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
| record_format | Article |
| series | Acta Cirúrgica Brasileira |
| spelling | doaj-art-9a3d4c22c4744fc9a66c2d46d20ccc9f2025-07-22T07:38:34ZengSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira1678-26742025-07-014010.1590/acb405325Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal modelThiago de Almeida Furtadohttps://orcid.org/0000-0003-0380-914XÁlvaro Cota Carvalhohttps://orcid.org/0009-0006-9998-3167Marcelo Lopes Furtadohttps://orcid.org/0000-0002-5103-5807Luiz Ronaldo Albertihttps://orcid.org/0000-0002-5229-3971Diego Paim de Carvalho Garciahttps://orcid.org/0000-0002-2921-653XABSTRACT Purpose: To evaluate the effectiveness of a new format of prophylactic mesh, with a new method of placement. Methods: Rabbits were randomly distributed into four groups: control rabbits without laparotomy group; sutured rabbits (SR); light-weight mesh rabbits (LWMR); and heavy-weight mesh rabbits (HWMR). The meshes were cut to a size of 10 cm in length by 1 cm in width. A longitudinal, median abdominal incision, 11 cm in length, was performed, followed by an incision over the linea alba, encompassing the entire thickness of the abdominal wall. On the 91st postoperative day, the animals were killed for linea alba scar evaluation. Results: There was a significant difference among the evaluated groups concerning elongation, maximum load, and elasticity modulus. HWMR and LWMR were statistically different from controls regarding elongation. As for the elasticity modulus, SR presented a higher mean when compared to the others. Microscopic visual analysis showed greater fibrotic scarring with a larger amount of implanted material in HWMR. Conclusion: The reinforcement of scars with polypropylene mesh does not increase tensile strength when compared to the use of sutures. Mesh implantation results in scar remodeling with greater fibrosis, leading to increased elongation. However, midline reinforcement using only sutures has greater elasticity than the groups reinforced with mesh.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100231&lng=en&tlng=enHernia, VentralModels, AnimalIncisional Hernia |
| spellingShingle | Thiago de Almeida Furtado Álvaro Cota Carvalho Marcelo Lopes Furtado Luiz Ronaldo Alberti Diego Paim de Carvalho Garcia Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model Acta Cirúrgica Brasileira Hernia, Ventral Models, Animal Incisional Hernia |
| title | Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model |
| title_full | Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model |
| title_fullStr | Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model |
| title_full_unstemmed | Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model |
| title_short | Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model |
| title_sort | biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh in an animal model |
| topic | Hernia, Ventral Models, Animal Incisional Hernia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100231&lng=en&tlng=en |
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