CCN5 Drives Leydig Cell Aging and Testicular Dysfunction: Insights into Fibrosis, Lipid Dysregulation, and Therapeutic Potential
Leydig cells’ (LCs’) senescence is an important reason for the decline of testicular function in elderly men. Cellular communication network factor 5 (CCN5) regulates lipid metabolism and cellular fibrosis through multiple mechanisms. However, its role in LCs’ aging and the underlying molecular mech...
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Main Authors: | Xiaoli Tan, Yanghua Xu, Ningjing Ou, Yuzhuo Chen, Wanyi Xia, Emily Xing, Ren Mo, Hao Bo, Zhitao Han, Jiarong Xu, Zepeng Dong, Yingbo Dai, Yuxin Tang, Liangyu Zhao |
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Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2025-01-01
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Series: | Research |
Online Access: | https://spj.science.org/doi/10.34133/research.0762 |
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