Status and Progress of Research on Metabolomics of Cervical Cancer

Cervical cancer is one of the most common gynecological malignant tumors in China. Given their lack of obviously early symptoms, more than half of patients with cervical cancer are diagnosed in the middle and late stages of this malignancy, resulting in poor prognosis. Finding new therapeutic target...

Full description

Saved in:
Bibliographic Details
Main Authors: Shaojun CHEN, Ling GAN, Xinkang CHEN, Lingling XIONG, Die LONG, Lulu CHEN, Mengzhuan WEI, Li HUA, Haixin HUANG
Format: Article
Language:Chinese
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-07-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1169
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839617183375687680
author Shaojun CHEN
Ling GAN
Xinkang CHEN
Lingling XIONG
Die LONG
Lulu CHEN
Mengzhuan WEI
Li HUA
Haixin HUANG
author_facet Shaojun CHEN
Ling GAN
Xinkang CHEN
Lingling XIONG
Die LONG
Lulu CHEN
Mengzhuan WEI
Li HUA
Haixin HUANG
author_sort Shaojun CHEN
collection DOAJ
description Cervical cancer is one of the most common gynecological malignant tumors in China. Given their lack of obviously early symptoms, more than half of patients with cervical cancer are diagnosed in the middle and late stages of this malignancy, resulting in poor prognosis. Finding new therapeutic targets is the current research direction. Metabolomics, as a new omics technology, is expected to provide new targets for tumor precision diagnosis and treatment through the analysis of the changes and potential mechanisms of metabolites in tumor occurrence and development by chromatography, mass spectrometry, and other technologies. Herein, we review the research methods of metabolomics; metabolic characteristics of cervical cancer; and progress of the research on metabolomics in cervical cancer diagnosis, curative effect prediction, and prognosis evaluation to provide new ideas for the precise diagnosis and treatment of cervical cancer.
format Article
id doaj-art-99b84d7cd58342dba3b876b1ad46a5f5
institution Matheson Library
issn 1000-8578
language zho
publishDate 2025-07-01
publisher Magazine House of Cancer Research on Prevention and Treatment
record_format Article
series Zhongliu Fangzhi Yanjiu
spelling doaj-art-99b84d7cd58342dba3b876b1ad46a5f52025-07-25T01:40:43ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782025-07-0152763063610.3971/j.issn.1000-8578.2025.24.116920241169Status and Progress of Research on Metabolomics of Cervical CancerShaojun CHEN0Ling GAN1Xinkang CHEN2Lingling XIONG3Die LONG4Lulu CHEN5Mengzhuan WEI6Li HUA7Haixin HUANG8Cancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCancer Center, The Fourth Affiliated Hospital of Guangxi Medical University/Liuzhou Workers' Hospital, Liuzhou 545005, ChinaCervical cancer is one of the most common gynecological malignant tumors in China. Given their lack of obviously early symptoms, more than half of patients with cervical cancer are diagnosed in the middle and late stages of this malignancy, resulting in poor prognosis. Finding new therapeutic targets is the current research direction. Metabolomics, as a new omics technology, is expected to provide new targets for tumor precision diagnosis and treatment through the analysis of the changes and potential mechanisms of metabolites in tumor occurrence and development by chromatography, mass spectrometry, and other technologies. Herein, we review the research methods of metabolomics; metabolic characteristics of cervical cancer; and progress of the research on metabolomics in cervical cancer diagnosis, curative effect prediction, and prognosis evaluation to provide new ideas for the precise diagnosis and treatment of cervical cancer.http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1169cervical cancermetabolomicsdiagnosispredictionprognosis
spellingShingle Shaojun CHEN
Ling GAN
Xinkang CHEN
Lingling XIONG
Die LONG
Lulu CHEN
Mengzhuan WEI
Li HUA
Haixin HUANG
Status and Progress of Research on Metabolomics of Cervical Cancer
Zhongliu Fangzhi Yanjiu
cervical cancer
metabolomics
diagnosis
prediction
prognosis
title Status and Progress of Research on Metabolomics of Cervical Cancer
title_full Status and Progress of Research on Metabolomics of Cervical Cancer
title_fullStr Status and Progress of Research on Metabolomics of Cervical Cancer
title_full_unstemmed Status and Progress of Research on Metabolomics of Cervical Cancer
title_short Status and Progress of Research on Metabolomics of Cervical Cancer
title_sort status and progress of research on metabolomics of cervical cancer
topic cervical cancer
metabolomics
diagnosis
prediction
prognosis
url http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1169
work_keys_str_mv AT shaojunchen statusandprogressofresearchonmetabolomicsofcervicalcancer
AT linggan statusandprogressofresearchonmetabolomicsofcervicalcancer
AT xinkangchen statusandprogressofresearchonmetabolomicsofcervicalcancer
AT linglingxiong statusandprogressofresearchonmetabolomicsofcervicalcancer
AT dielong statusandprogressofresearchonmetabolomicsofcervicalcancer
AT luluchen statusandprogressofresearchonmetabolomicsofcervicalcancer
AT mengzhuanwei statusandprogressofresearchonmetabolomicsofcervicalcancer
AT lihua statusandprogressofresearchonmetabolomicsofcervicalcancer
AT haixinhuang statusandprogressofresearchonmetabolomicsofcervicalcancer