THE EFFECT OF EXOGENOUS GLUCOSAMINE HYDROCHLORIDE AND CHONDROITIN SULFATE ON THE SYNTHESIS OF NUCLEIC ACIDS IN PERIODONTAL TISSUES DURING EXPERIMENTAL INFLAMMATION

The article discusses the study of effect of exogenous glucosamine hydrochloride and chondroitin sulfate on the synthesis of nucleic acids in experimental gingivitis. Experimental model of gingivitis were formed at 40 white Wistar rats, were formed: the control and main groups, further investigated...

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Bibliographic Details
Main Authors: N. I. BYKOVA, A. V. ODOLSKI, V. A. GRIGORYAN
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2017-06-01
Series:Кубанский научный медицинский вестник
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Online Access:https://ksma.elpub.ru/jour/article/view/697
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Summary:The article discusses the study of effect of exogenous glucosamine hydrochloride and chondroitin sulfate on the synthesis of nucleic acids in experimental gingivitis. Experimental model of gingivitis were formed at 40 white Wistar rats, were formed: the control and main groups, further investigated the periodontium in 20 intact animals. Evaluation of the effect of exogenous glucosamine hydrochloride and chondroitin sulfate on the synthesis of nucleic acids in experimental gingivitis conducted at the level of morpho-functional activity of fibroblasts, which was judged by the degree of dispersion of the chromatin. The study found a positive effect of exogenous glucosamine hydrochloride and chondroitin sulfate on the course of experimental gingivitis, which is manifested by increasing the morphofunctional activity of fibroblasts.
ISSN:1608-6228
2541-9544