Unraveling the relationships of phthalate exposure, long-term trajectories for novel insulin resistance biomarkers and accelerated pubertal onset in children

Unraveling the relationships of phthalate exposure, long-term trajectories for novel insulin resistance biomarkers and accelerated pubertal onset in children

Phthalates (PAEs) exposure and triglyceride-glucose (TyG) index—an indicator of insulin resistance (IR), remains not fully understood. To investigate the predictive and mediating role of IR markers in associations between PAEs exposure and puberty initiation, adjusting for sex hormones. A cohort was...

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Bibliographic Details
Main Authors: Jieyu Liu, Di Gao, Yanhui Li, Manman Chen, Xinli Song, Yi Zhang, Jianuo Jiang, Ruolin Wang, Ziqi Dong, Li Chen, Yang Qin, Zhiying Song, Xinxin Wang, Yanhui Dong, Zhiyong Zou, Jun Ma
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Phthalates, insulin resistance surrogates
Puberty onset
Cohort
Children
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325010115
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