From theory to platelets: unraveling the history and complexities of biased signaling

Abstract: Biased signaling refers to a phenomenon where a ligand preferentially activates 1 signaling pathway over another at the same receptor. It is best described for ligands that selectively activate G protein–coupled receptors through G protein or β-arrestin pathways. The concept of biased sign...

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Bibliographic Details
Main Authors: NaShea C. Kendrick, Grace H. Huang, Germaine J. Harvey, Marvin T. Nieman
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Blood Vessels, Thrombosis & Hemostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2950327225000300
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