Amino acid supplementation supports growth and reproductive development under dietary restriction
IntroductionNutritional status influences developmental processes, including sexual maturation. While the effects of macronutrients on reproductive development are well studied, the role of specific amino acid composition in ovarian and follicular development in birds remains less explored. Here, we...
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Animal Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fanim.2025.1622877/full |
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| author | Sawadi F. Ndunguru Sawadi F. Ndunguru Sawadi F. Ndunguru Gebrehaweria K. Reda Gebrehaweria K. Reda Gebrehaweria K. Reda Brigitta Csernus Gabriella Gulyás Renáta Knop Csaba Szabó Ádám Z. Lendvai Levente Czeglédi |
| author_facet | Sawadi F. Ndunguru Sawadi F. Ndunguru Sawadi F. Ndunguru Gebrehaweria K. Reda Gebrehaweria K. Reda Gebrehaweria K. Reda Brigitta Csernus Gabriella Gulyás Renáta Knop Csaba Szabó Ádám Z. Lendvai Levente Czeglédi |
| author_sort | Sawadi F. Ndunguru |
| collection | DOAJ |
| description | IntroductionNutritional status influences developmental processes, including sexual maturation. While the effects of macronutrients on reproductive development are well studied, the role of specific amino acid composition in ovarian and follicular development in birds remains less explored. Here, we investigated the impact of dietary restriction and amino acid supplementation on growth and reproductive development of Japanese quail (Coturnix japonica).MethodsBirds were assigned to five dietary treatments: control (ad libitum), 20% dietary restriction (DR20), and DR20 supplemented with methionine (DR20+Met), leucine (DR20+Leu) or both (DR20+Leu+Met) at levels 20% above the recommended nutrient content.Results and discussionDietary restriction reduced body mass, ovary mass, ovary index, and total antioxidant capacity without affecting hierarchical follicle counts or size. However, supplementation with either amino acid improved these parameters from dietary restriction to the control levels. Furthermore, methionine supplementation alone or combination of methionine and leucine significantly increased follicle numbers, whereas leucine alone had no effect on hierarchical follicle numbers. Our findings underscore the importance of amino acids in mitigating the adverse effects of dietary restriction on growth, reproduction, and oxidative balance in birds at the onset of reproductive maturation. |
| format | Article |
| id | doaj-art-99548dd83c7e438c8683979c20b0c60d |
| institution | Matheson Library |
| issn | 2673-6225 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Animal Science |
| spelling | doaj-art-99548dd83c7e438c8683979c20b0c60d2025-07-04T14:46:13ZengFrontiers Media S.A.Frontiers in Animal Science2673-62252025-07-01610.3389/fanim.2025.16228771622877Amino acid supplementation supports growth and reproductive development under dietary restrictionSawadi F. Ndunguru0Sawadi F. Ndunguru1Sawadi F. Ndunguru2Gebrehaweria K. Reda3Gebrehaweria K. Reda4Gebrehaweria K. Reda5Brigitta Csernus6Gabriella Gulyás7Renáta Knop8Csaba Szabó9Ádám Z. Lendvai10Levente Czeglédi11Department of Animal Science, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryDoctoral School of Animal Science, University of Debrecen, Debrecen, HungaryDepartment of Evolutionary Zoology and Human Biology, University of Debrecen, Debrecen, HungaryDepartment of Animal Science, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryDoctoral School of Animal Science, University of Debrecen, Debrecen, HungaryDepartment of Evolutionary Zoology and Human Biology, University of Debrecen, Debrecen, HungaryDepartment of Evolutionary Zoology and Human Biology, University of Debrecen, Debrecen, HungaryDepartment of Animal Science, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryDepartment of Animal Science, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryDepartment of Animal Nutrition and Physiology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryDepartment of Evolutionary Zoology and Human Biology, University of Debrecen, Debrecen, HungaryDepartment of Animal Science, Institute of Animal Science, Biotechnology and Nature Conservation, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Debrecen, HungaryIntroductionNutritional status influences developmental processes, including sexual maturation. While the effects of macronutrients on reproductive development are well studied, the role of specific amino acid composition in ovarian and follicular development in birds remains less explored. Here, we investigated the impact of dietary restriction and amino acid supplementation on growth and reproductive development of Japanese quail (Coturnix japonica).MethodsBirds were assigned to five dietary treatments: control (ad libitum), 20% dietary restriction (DR20), and DR20 supplemented with methionine (DR20+Met), leucine (DR20+Leu) or both (DR20+Leu+Met) at levels 20% above the recommended nutrient content.Results and discussionDietary restriction reduced body mass, ovary mass, ovary index, and total antioxidant capacity without affecting hierarchical follicle counts or size. However, supplementation with either amino acid improved these parameters from dietary restriction to the control levels. Furthermore, methionine supplementation alone or combination of methionine and leucine significantly increased follicle numbers, whereas leucine alone had no effect on hierarchical follicle numbers. Our findings underscore the importance of amino acids in mitigating the adverse effects of dietary restriction on growth, reproduction, and oxidative balance in birds at the onset of reproductive maturation.https://www.frontiersin.org/articles/10.3389/fanim.2025.1622877/fullamino acidsdietary restrictionJapanese quailovary folliclestotal antioxidant capacity |
| spellingShingle | Sawadi F. Ndunguru Sawadi F. Ndunguru Sawadi F. Ndunguru Gebrehaweria K. Reda Gebrehaweria K. Reda Gebrehaweria K. Reda Brigitta Csernus Gabriella Gulyás Renáta Knop Csaba Szabó Ádám Z. Lendvai Levente Czeglédi Amino acid supplementation supports growth and reproductive development under dietary restriction Frontiers in Animal Science amino acids dietary restriction Japanese quail ovary follicles total antioxidant capacity |
| title | Amino acid supplementation supports growth and reproductive development under dietary restriction |
| title_full | Amino acid supplementation supports growth and reproductive development under dietary restriction |
| title_fullStr | Amino acid supplementation supports growth and reproductive development under dietary restriction |
| title_full_unstemmed | Amino acid supplementation supports growth and reproductive development under dietary restriction |
| title_short | Amino acid supplementation supports growth and reproductive development under dietary restriction |
| title_sort | amino acid supplementation supports growth and reproductive development under dietary restriction |
| topic | amino acids dietary restriction Japanese quail ovary follicles total antioxidant capacity |
| url | https://www.frontiersin.org/articles/10.3389/fanim.2025.1622877/full |
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