Place of imidazoline receptor agonists in the treatment of hypertension
The review is devoted to selective I1-imidazoline-receptor agonists. An analysis of Russian and foreign studies is presented, the results of which indicate that this drug class not only provides adequate and long-term control of blood pressure, but also has a number of favorable metabolic effects. T...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2022-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3129 |
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| author | D. V. Nebieridze A. S. Safaryan |
| author_facet | D. V. Nebieridze A. S. Safaryan |
| author_sort | D. V. Nebieridze |
| collection | DOAJ |
| description | The review is devoted to selective I1-imidazoline-receptor agonists. An analysis of Russian and foreign studies is presented, the results of which indicate that this drug class not only provides adequate and long-term control of blood pressure, but also has a number of favorable metabolic effects. Therefore, it contributes to reducing insulin resistance (weight loss) and has organ protective properties (endothelial function improvement, left ventricular hypertrophy regression, microalbuminuria reduction). At the same time, selective I1-imidazoline-receptor agonists are much less likely to cause side effects characteristic of old-generation sympatholytic agents. This class of drugs is invariably included in Russian guidelines for the diagnosis and treatment of hypertension. |
| format | Article |
| id | doaj-art-99197b9dd9284a20a168045ff9b4082d |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2022-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-99197b9dd9284a20a168045ff9b4082d2025-08-04T12:50:27Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252022-01-0120810.15829/1728-8800-2021-31292418Place of imidazoline receptor agonists in the treatment of hypertensionD. V. Nebieridze0A. S. Safaryan1National Research Center for Therapy and Preventive MedicineNational Research Center for Therapy and Preventive MedicineThe review is devoted to selective I1-imidazoline-receptor agonists. An analysis of Russian and foreign studies is presented, the results of which indicate that this drug class not only provides adequate and long-term control of blood pressure, but also has a number of favorable metabolic effects. Therefore, it contributes to reducing insulin resistance (weight loss) and has organ protective properties (endothelial function improvement, left ventricular hypertrophy regression, microalbuminuria reduction). At the same time, selective I1-imidazoline-receptor agonists are much less likely to cause side effects characteristic of old-generation sympatholytic agents. This class of drugs is invariably included in Russian guidelines for the diagnosis and treatment of hypertension.https://cardiovascular.elpub.ru/jour/article/view/3129imidazoline receptor agonistsinsulin resistanceantihypertensive effectmetabolic effectsorgan protection |
| spellingShingle | D. V. Nebieridze A. S. Safaryan Place of imidazoline receptor agonists in the treatment of hypertension Кардиоваскулярная терапия и профилактика imidazoline receptor agonists insulin resistance antihypertensive effect metabolic effects organ protection |
| title | Place of imidazoline receptor agonists in the treatment of hypertension |
| title_full | Place of imidazoline receptor agonists in the treatment of hypertension |
| title_fullStr | Place of imidazoline receptor agonists in the treatment of hypertension |
| title_full_unstemmed | Place of imidazoline receptor agonists in the treatment of hypertension |
| title_short | Place of imidazoline receptor agonists in the treatment of hypertension |
| title_sort | place of imidazoline receptor agonists in the treatment of hypertension |
| topic | imidazoline receptor agonists insulin resistance antihypertensive effect metabolic effects organ protection |
| url | https://cardiovascular.elpub.ru/jour/article/view/3129 |
| work_keys_str_mv | AT dvnebieridze placeofimidazolinereceptoragonistsinthetreatmentofhypertension AT assafaryan placeofimidazolinereceptoragonistsinthetreatmentofhypertension |