Therapeutic Potential of 7,8-Dimethoxycoumarin in Tumor Necrosis Factor-Alpha-Induced Trigeminal Neuralgia in a Rat Model

Therapeutic Potential of 7,8-Dimethoxycoumarin in Tumor Necrosis Factor-Alpha-Induced Trigeminal Neuralgia in a Rat Model

Trigeminal neuralgia is a chronic pain disorder due to neuronal damage. The present study was designed to investigate the effect of 7,8-dimethoxy coumarin (DMC) in a rat model of trigeminal neuralgia. The neuropathic pain was induced by the single endoneural injection of tumor necrosis factor-alpha...

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Bibliographic Details
Main Authors: Nallupillai Paramakrishnan, Kanthiraj Raadhika, Sumitha Elayaperumal, Yuvaraj Sivamani, Yamunna Paramaswaran, Lim Joe Siang, Thiagharajan Venkata Rathina Kumar, Khian Giap Lim, Muthusamy Ramesh, Arunachalam Muthuraman
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Current Issues in Molecular Biology
Subjects:
allodynia
endoneural injection
hematoxylin staining
hyperalgesia
reduced glutathione
Online Access:https://www.mdpi.com/1467-3045/47/7/518
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