Comparative Evaluation of Allergodiagnostic of Tuberculosis in Children

The comparative analysis of results of the tuberculin skin test (TST) and of the skin test with the recombinant tuberculosis allergen (Diaskintest - DST) in 7978 children with active tuberculosis revealed for the first time in 2013 - 2014 was carried out. The negative DST result and positive TST res...

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Bibliographic Details
Main Authors: I. V. Mikheeva, E. Yu. Burdova, A. A. Melnikova
Format: Article
Language:Russian
Published: Numikom LLC 2016-06-01
Series:Эпидемиология и вакцинопрофилактика
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Online Access:https://www.epidemvac.ru/jour/article/view/163
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Summary:The comparative analysis of results of the tuberculin skin test (TST) and of the skin test with the recombinant tuberculosis allergen (Diaskintest - DST) in 7978 children with active tuberculosis revealed for the first time in 2013 - 2014 was carried out. The negative DST result and positive TST result are observed at 551 (6.91%) of patients. 92 patients (1.15%) had negative both tests, and at 98 people (1.23%) DST has yielded positive result, PM - negative. Other patients had positive both tests. In general, by means of DST tuberculosis initially hasn't been revealed at 643 (8.06%) patients, and by means of TST - at 190 (2.38%) patients. The difference is statistically reliable (t = 9.16; P < 0.05). Dynamics of tests results at patients with active tuberculosis was studied. The result of DST remained negative for a year in18.7% of patients, in 26,7% of patients with initially negative DST the result became positive in 3 months, in 2.7% - a year after the first testing. Tuberculosis of various forms and localizations, including TB+, was diagnosed for children with initially negative results of DST and positive TST.
ISSN:2073-3046
2619-0494