Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry
Aim. To study the long-term survival of patients with cerebrovascular accident, depending on sex and age.Material and methods. The outpatient part of the REGION-M registry (patients with cerebrovascular accident, hospitalized in a Moscow hospital) included 684 patients assigned to the City Polyclini...
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«SILICEA-POLIGRAF» LLC
2023-09-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3596 |
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| author | S. N. Tolpygina A. V. Zagrebelny M. I. Chernysheva N. P. Kutishenko V. P. Voronina N. A. Dmitrieva O. V. Lerman Yu. V. Lukina M. M. Lukyanov E. Yu. Okshina N. E. Parsadanyan S. Yu. Martsevich O. M. Drapkina |
| author_facet | S. N. Tolpygina A. V. Zagrebelny M. I. Chernysheva N. P. Kutishenko V. P. Voronina N. A. Dmitrieva O. V. Lerman Yu. V. Lukina M. M. Lukyanov E. Yu. Okshina N. E. Parsadanyan S. Yu. Martsevich O. M. Drapkina |
| author_sort | S. N. Tolpygina |
| collection | DOAJ |
| description | Aim. To study the long-term survival of patients with cerebrovascular accident, depending on sex and age.Material and methods. The outpatient part of the REGION-M registry (patients with cerebrovascular accident, hospitalized in a Moscow hospital) included 684 patients assigned to the City Polyclinic № 64 (Moscow), discharged from the F. I. Inozemtsev City Clinical Hospital (Moscow) in the period from January 1, 2012 to April 30, 2017 with a diagnosis of stroke, which were divided into 5 age groups: group 1 — ≤50 years, n=72 (10,5%), group 2 — 51-60 years old, n=122 (17,8%), group 3 — 61-70 years old, n=156 (22,8%), group 4 — 71-80 years old, n=185 (27,0%) and group 5 — ≥81 years old, n=149 (21,8%). The survival of patients was assessed at the 2nd and 3rd stages after 4,2 (2,4-5,6) and 5,5 (2,4-7,0) years.Results. The mortality of patients in the long-term follow-up period significantly increased with age. There were following mortality rate for stages 2 and 3 stages: 18-50 years old — 8,3 and 22,2%, 51-60 years old — 18 and 36,9%, 61-70 years old — 41 and 56,4%, 71-80 years old — 54,1 and 73%, >81 years — 76,5 and 87,9% (p<0,0001 for all groups). At stages 2 and 3, mortality among men was higher than among women in groups 2-4, below in group 1 and did not differ in the oldest age group. In multivariate analysis, the following factors had prognostic significance: age — hazard ratio (HR) of death, 1,035 (95% confidence interval (CI): 1,029-1,041, p=0,001), sex — HR, 0,720 (95% CI: 0,43-0,123, p=0,001) and disability before stroke — HR, 0,999 (95% CI: 0,998-1,000, p=0,002).Conclusion. In long-term follow-up, the mortality of patients with cerebrovascular accident was significantly higher in older age groups, as well as among men. |
| format | Article |
| id | doaj-art-97811d9fe15a4e6fbe9255a54a359d8b |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2023-09-01 |
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| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-97811d9fe15a4e6fbe9255a54a359d8b2025-08-04T12:50:30Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252023-09-0122710.15829/1728-8800-2023-35962763Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registryS. N. Tolpygina0A. V. Zagrebelny1M. I. Chernysheva2N. P. Kutishenko3V. P. Voronina4N. A. Dmitrieva5O. V. Lerman6Yu. V. Lukina7M. M. Lukyanov8E. Yu. Okshina9N. E. Parsadanyan10S. Yu. Martsevich11O. M. Drapkina12National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive Medicine; City polyclinic № 218National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineCity polyclinic № 218National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineAim. To study the long-term survival of patients with cerebrovascular accident, depending on sex and age.Material and methods. The outpatient part of the REGION-M registry (patients with cerebrovascular accident, hospitalized in a Moscow hospital) included 684 patients assigned to the City Polyclinic № 64 (Moscow), discharged from the F. I. Inozemtsev City Clinical Hospital (Moscow) in the period from January 1, 2012 to April 30, 2017 with a diagnosis of stroke, which were divided into 5 age groups: group 1 — ≤50 years, n=72 (10,5%), group 2 — 51-60 years old, n=122 (17,8%), group 3 — 61-70 years old, n=156 (22,8%), group 4 — 71-80 years old, n=185 (27,0%) and group 5 — ≥81 years old, n=149 (21,8%). The survival of patients was assessed at the 2nd and 3rd stages after 4,2 (2,4-5,6) and 5,5 (2,4-7,0) years.Results. The mortality of patients in the long-term follow-up period significantly increased with age. There were following mortality rate for stages 2 and 3 stages: 18-50 years old — 8,3 and 22,2%, 51-60 years old — 18 and 36,9%, 61-70 years old — 41 and 56,4%, 71-80 years old — 54,1 and 73%, >81 years — 76,5 and 87,9% (p<0,0001 for all groups). At stages 2 and 3, mortality among men was higher than among women in groups 2-4, below in group 1 and did not differ in the oldest age group. In multivariate analysis, the following factors had prognostic significance: age — hazard ratio (HR) of death, 1,035 (95% confidence interval (CI): 1,029-1,041, p=0,001), sex — HR, 0,720 (95% CI: 0,43-0,123, p=0,001) and disability before stroke — HR, 0,999 (95% CI: 0,998-1,000, p=0,002).Conclusion. In long-term follow-up, the mortality of patients with cerebrovascular accident was significantly higher in older age groups, as well as among men.https://cardiovascular.elpub.ru/jour/article/view/3596cerebrovascular accidentcerebral stroketransient ischemic attackregistrylong-term survivalmortalityage groupssex |
| spellingShingle | S. N. Tolpygina A. V. Zagrebelny M. I. Chernysheva N. P. Kutishenko V. P. Voronina N. A. Dmitrieva O. V. Lerman Yu. V. Lukina M. M. Lukyanov E. Yu. Okshina N. E. Parsadanyan S. Yu. Martsevich O. M. Drapkina Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry Кардиоваскулярная терапия и профилактика cerebrovascular accident cerebral stroke transient ischemic attack registry long-term survival mortality age groups sex |
| title | Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry |
| title_full | Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry |
| title_fullStr | Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry |
| title_full_unstemmed | Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry |
| title_short | Long-term survival of patients with cerebrovascular accident, depending on sex and age: data from the REGION-M registry |
| title_sort | long term survival of patients with cerebrovascular accident depending on sex and age data from the region m registry |
| topic | cerebrovascular accident cerebral stroke transient ischemic attack registry long-term survival mortality age groups sex |
| url | https://cardiovascular.elpub.ru/jour/article/view/3596 |
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