The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period

The aim was to identify the risk factors contributed to adverse outcome of myocardial infarction (MI) in the acute period of the disease at a prehospital stage.Materials and methods. The study included the call cards of specialized resuscitation and anesthesia units of the budgetary institution A. S...

Full description

Saved in:
Bibliographic Details
Main Authors: A. E. Zakharova, E. A. Spiridonova, N. F. Plavunov, Yu. V. Nikiforov, E. D. Avdeeva, M. B. Lagutin
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2016-02-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1511
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839578445937377280
author A. E. Zakharova
E. A. Spiridonova
N. F. Plavunov
Yu. V. Nikiforov
E. D. Avdeeva
M. B. Lagutin
author_facet A. E. Zakharova
E. A. Spiridonova
N. F. Plavunov
Yu. V. Nikiforov
E. D. Avdeeva
M. B. Lagutin
author_sort A. E. Zakharova
collection DOAJ
description The aim was to identify the risk factors contributed to adverse outcome of myocardial infarction (MI) in the acute period of the disease at a prehospital stage.Materials and methods. The study included the call cards of specialized resuscitation and anesthesia units of the budgetary institution A. S. Puchkov «Station of emergency medical care», to patients with complicated MI. The study included two groups of patients. The first group comprized of patients with complicated MI which resulted in circulatory arrest (n=184), the second group (the group of comparison) included patients with com plicated MI without the outcome in circulatory arrest (n=271). Statistical processing of the material: significance of differences between two binomial observations was evaluated by the Barnard's Exact Test.The results of the research. The presence of risk of MI complication as a stopping of blood circulation was confirmed in patients of the age group of 40—60 years (P=0.01). Patients with MI complicated by a circulatory arrest was characterized by a significantly greater intensity of pain syndrome (the pain intensity of 9—10 points was typ ical for 11,2% and 3% of patients of the group with circulatory arrest and the group of comparison, respectively; P< 0.001). The combination of clinical manifestations of alveolar pulmonary edema and arrhythmia occurred in 50% of patients with circulatory arrest, resulted in poor prognosis (the frequency of same parameters in a control group was 28,7%, P=0.018). Tachysystolic arrhythmia was the most common form of alteration at a circulatory arrest.Conclusions. The risk factors for MI adverse outcome in acute period included age from 40 to 60 years, pain of high intensity, presence of cardiogenic shock in combination with alveolar pulmonary edema and tachyarrhythmia.
format Article
id doaj-art-97392b4e289e4422b45b5eba68c1b77c
institution Matheson Library
issn 1813-9779
2411-7110
language English
publishDate 2016-02-01
publisher Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
record_format Article
series Общая реаниматология
spelling doaj-art-97392b4e289e4422b45b5eba68c1b77c2025-08-04T10:40:43ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102016-02-01121506010.15360/1813-9779-2016-1-50-601489The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute PeriodA. E. Zakharova0E. A. Spiridonova1N. F. Plavunov2Yu. V. Nikiforov3E. D. Avdeeva4M. B. Lagutin5A. S. Puchkov Station of emergency medical care, Department of Health of MoscowD. Rogachev Federal scientific clinical centre of pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia; A.I. Evdokimov Moscow State University of medicine and dentistry, Ministry of Health of RussiaA. S. Puchkov Station of emergency medical care, Department of Health of Moscow; A.I. Evdokimov Moscow State University of medicine and dentistry, Ministry of Health of RussiaV. A. Negovsky Research Institute of General ReanimatologyA.I. Evdokimov Moscow State University of medicine and dentistry, Ministry of Health of RussiaM. V. Lomonosov Moscow State UniversityThe aim was to identify the risk factors contributed to adverse outcome of myocardial infarction (MI) in the acute period of the disease at a prehospital stage.Materials and methods. The study included the call cards of specialized resuscitation and anesthesia units of the budgetary institution A. S. Puchkov «Station of emergency medical care», to patients with complicated MI. The study included two groups of patients. The first group comprized of patients with complicated MI which resulted in circulatory arrest (n=184), the second group (the group of comparison) included patients with com plicated MI without the outcome in circulatory arrest (n=271). Statistical processing of the material: significance of differences between two binomial observations was evaluated by the Barnard's Exact Test.The results of the research. The presence of risk of MI complication as a stopping of blood circulation was confirmed in patients of the age group of 40—60 years (P=0.01). Patients with MI complicated by a circulatory arrest was characterized by a significantly greater intensity of pain syndrome (the pain intensity of 9—10 points was typ ical for 11,2% and 3% of patients of the group with circulatory arrest and the group of comparison, respectively; P< 0.001). The combination of clinical manifestations of alveolar pulmonary edema and arrhythmia occurred in 50% of patients with circulatory arrest, resulted in poor prognosis (the frequency of same parameters in a control group was 28,7%, P=0.018). Tachysystolic arrhythmia was the most common form of alteration at a circulatory arrest.Conclusions. The risk factors for MI adverse outcome in acute period included age from 40 to 60 years, pain of high intensity, presence of cardiogenic shock in combination with alveolar pulmonary edema and tachyarrhythmia.https://www.reanimatology.com/rmt/article/view/1511acute myocardial infarctioncirculatory arrest
spellingShingle A. E. Zakharova
E. A. Spiridonova
N. F. Plavunov
Yu. V. Nikiforov
E. D. Avdeeva
M. B. Lagutin
The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
Общая реаниматология
acute myocardial infarction
circulatory arrest
title The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
title_full The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
title_fullStr The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
title_full_unstemmed The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
title_short The Analysis of the Risk Factors of Adverse Prognosis of Myocardial Infarction in the Acute Period
title_sort analysis of the risk factors of adverse prognosis of myocardial infarction in the acute period
topic acute myocardial infarction
circulatory arrest
url https://www.reanimatology.com/rmt/article/view/1511
work_keys_str_mv AT aezakharova theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT easpiridonova theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT nfplavunov theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT yuvnikiforov theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT edavdeeva theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT mblagutin theanalysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT aezakharova analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT easpiridonova analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT nfplavunov analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT yuvnikiforov analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT edavdeeva analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod
AT mblagutin analysisoftheriskfactorsofadverseprognosisofmyocardialinfarctionintheacuteperiod