Frequency of HLA Antigens in a Sample of Iraqi Brucellosis Patients
Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0....
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Format: | Article |
Language: | English |
Published: |
University of Baghdad, College of Science for Women
2012-03-01
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Series: | مجلة بغداد للعلوم |
Subjects: | |
Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1337 |
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Summary: | Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0.001) increased frequency of HLA-DR8 (41.18 vs. 10.0%) in the patients . A significant increased percentage of CD8+ lymphocytes was also increased in the patients (25.15 vs. 22.0%; P = 0.006), while CD3+ lymphocytes were significantly decreased (75.1 vs. 79.4%; P = 0.02). |
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ISSN: | 2078-8665 2411-7986 |