Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma
Aim. Assessment of the utility and advantage of videoendoscopic inguinal femoral lymphadenectomy (VE-LAD) over the standard open technique (OLAD) in patients with malignant skin melanoma and metastatic lesions of regional inguinal and/or femoral lymph nodes.Materials and methods. The Saint-Petersbur...
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Bashkir State Medical University
2021-05-01
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| Series: | Креативная хирургия и онкология |
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| Online Access: | https://www.surgonco.ru/jour/article/view/583 |
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| author | V. V. Egorenkov F. V. Moiseenko N. M. Volkov M. S. Molchanov M. S. Ravkina N. Kh. Abduloeva A. V. Linets V. R. Khairutdinov A. M. Ibragimov V. M. Moiseyenko |
| author_facet | V. V. Egorenkov F. V. Moiseenko N. M. Volkov M. S. Molchanov M. S. Ravkina N. Kh. Abduloeva A. V. Linets V. R. Khairutdinov A. M. Ibragimov V. M. Moiseyenko |
| author_sort | V. V. Egorenkov |
| collection | DOAJ |
| description | Aim. Assessment of the utility and advantage of videoendoscopic inguinal femoral lymphadenectomy (VE-LAD) over the standard open technique (OLAD) in patients with malignant skin melanoma and metastatic lesions of regional inguinal and/or femoral lymph nodes.Materials and methods. The Saint-Petersburg Clinical Research Centre for Specialty Medical Aid in Oncology managed 86 inguinal femoral LADs in melanoma patients over 2013–2016. VE-LAD was rendered in 48 (54.7 %) cases, and OLAD otherwise.Results and discussion. A total of 72 patients were included in the study. VE-LAD was performed in 48 (54.7 %) cases, and OLAD otherwise. An average VE-LAD duration was 90 (60 to 160) min. Severe complications were observed in 4/48 (8 %) VE-LAD and 16/24 (66 %) OLAD cases, which reveals a significantly lower complication rate in the study cohort (chi-square p > 0.000). Lymphorrhoea was shorter in the study cohort (> 7 days in 5 patients vs. 3/24 and > 14 days only in 11/24 OLAD cases; chi-square p > 0.000). No significant differences in relapse-free survival were observed between the cohorts, with higher absolute values of 22.6 months in the VE-LAD (95 % CI 14.8–30.4, p = 0.087) vs. 9.4 months (95 % CI 0.0–18.9, p = 0.087) in OLAD cohort. A median OS was 52.3 months (95 % CI 30.5–74.1, p = 0.996) in the VE-LAD vs. 39.9 months (95 % CI 30.6–49.2, p = 0.996) in OLAD cohort.Conclusion. Videoendoscopic inguinal femoral lymphadenectomy allows a radical inguinal femoral lymph node removal alike in conventional surgical dissection. Our results indicate the method performance towards reduced postoperative wound complications. The oncological indicators are comparable to the traditional surgery cohort. |
| format | Article |
| id | doaj-art-964b56bc85de4a31b51aae9d1931e327 |
| institution | Matheson Library |
| issn | 2076-3093 2307-0501 |
| language | English |
| publishDate | 2021-05-01 |
| publisher | Bashkir State Medical University |
| record_format | Article |
| series | Креативная хирургия и онкология |
| spelling | doaj-art-964b56bc85de4a31b51aae9d1931e3272025-08-03T19:48:55ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012021-05-0111213814310.24060/2076-3093-2021-11-2-138-143428Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin MelanomaV. V. Egorenkov0F. V. Moiseenko1N. M. Volkov2M. S. Molchanov3M. S. Ravkina4N. Kh. Abduloeva5A. V. Linets6V. R. Khairutdinov7A. M. Ibragimov8V. M. Moiseyenko9St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic); I.I. Mechnikov North-Western State Medical University; N.N. Petrov National Medical Research Centre of OncologySt. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)I.I. Mechnikov North-Western State Medical UniversityS.M. Kirov Military Medical AcademySt. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)St. Petersburg Clinical Research and Practical Center for Specialized Types of Medical Care (Oncologic)Aim. Assessment of the utility and advantage of videoendoscopic inguinal femoral lymphadenectomy (VE-LAD) over the standard open technique (OLAD) in patients with malignant skin melanoma and metastatic lesions of regional inguinal and/or femoral lymph nodes.Materials and methods. The Saint-Petersburg Clinical Research Centre for Specialty Medical Aid in Oncology managed 86 inguinal femoral LADs in melanoma patients over 2013–2016. VE-LAD was rendered in 48 (54.7 %) cases, and OLAD otherwise.Results and discussion. A total of 72 patients were included in the study. VE-LAD was performed in 48 (54.7 %) cases, and OLAD otherwise. An average VE-LAD duration was 90 (60 to 160) min. Severe complications were observed in 4/48 (8 %) VE-LAD and 16/24 (66 %) OLAD cases, which reveals a significantly lower complication rate in the study cohort (chi-square p > 0.000). Lymphorrhoea was shorter in the study cohort (> 7 days in 5 patients vs. 3/24 and > 14 days only in 11/24 OLAD cases; chi-square p > 0.000). No significant differences in relapse-free survival were observed between the cohorts, with higher absolute values of 22.6 months in the VE-LAD (95 % CI 14.8–30.4, p = 0.087) vs. 9.4 months (95 % CI 0.0–18.9, p = 0.087) in OLAD cohort. A median OS was 52.3 months (95 % CI 30.5–74.1, p = 0.996) in the VE-LAD vs. 39.9 months (95 % CI 30.6–49.2, p = 0.996) in OLAD cohort.Conclusion. Videoendoscopic inguinal femoral lymphadenectomy allows a radical inguinal femoral lymph node removal alike in conventional surgical dissection. Our results indicate the method performance towards reduced postoperative wound complications. The oncological indicators are comparable to the traditional surgery cohort.https://www.surgonco.ru/jour/article/view/583lymphatic metastasesmetastatic skin melanomasentinel lymph nodelymphadenectomyvideo endoscopypostoperative complications |
| spellingShingle | V. V. Egorenkov F. V. Moiseenko N. M. Volkov M. S. Molchanov M. S. Ravkina N. Kh. Abduloeva A. V. Linets V. R. Khairutdinov A. M. Ibragimov V. M. Moiseyenko Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma Креативная хирургия и онкология lymphatic metastases metastatic skin melanoma sentinel lymph node lymphadenectomy video endoscopy postoperative complications |
| title | Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma |
| title_full | Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma |
| title_fullStr | Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma |
| title_full_unstemmed | Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma |
| title_short | Efficacy of Videoendoscopic Inguinal Femoral Lymphadenectomy for Management of Metastatic Skin Melanoma |
| title_sort | efficacy of videoendoscopic inguinal femoral lymphadenectomy for management of metastatic skin melanoma |
| topic | lymphatic metastases metastatic skin melanoma sentinel lymph node lymphadenectomy video endoscopy postoperative complications |
| url | https://www.surgonco.ru/jour/article/view/583 |
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