Immediate and Long-term Results of Stenting of the Unprotected Left Coronary Artery Trunk in Patients with Stable Coronary Heart Disease

Objective. To assess the immediate and long-term results of stenting of the unprotected left coronary artery (LCA) trunk in patients, by using different types of drug-eluting stents.Material and methods. The follow-up covered 282 patients who had undergone stenting of the unprotected LCA trunk. The...

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Main Authors: G. K. Arutyunyan, S. I. Provatorov, N. S. Zhukova, A. S. Tereshchenko, D. V. Ognerubov, I. V. Emel’yanov, I. V. Krasnoshchekov, A. N. Samko
Format: Article
Language:English
Published: Luchevaya Diagnostika, LLC 2019-05-01
Series:Вестник рентгенологии и радиологии
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Online Access:https://www.russianradiology.ru/jour/article/view/446
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Summary:Objective. To assess the immediate and long-term results of stenting of the unprotected left coronary artery (LCA) trunk in patients, by using different types of drug-eluting stents.Material and methods. The follow-up covered 282 patients who had undergone stenting of the unprotected LCA trunk. The mean follow-up was 34.6 [33.9; 35.3] months. The patients were divided into groups according to the type of a first-, second-, and third-generation implanted stent.Results. The incidence of adverse cardiovascular events in the patients of Group 1 was significantly higher than in those in Groups 2 and 3 (29 and 7.6%, p<0.0001). The incidence of thrombosis of first-generation stents (7.0%) was significantly higher than that of second- and third-generation ones (1.6%) (p=0.02). The incidence of adverse cardiovascular events was comparable between Groups 2 and 3, despite a shorter duration of dual antiplatelet therapy in the third-generation stent group. The absence of stent postdilatation in the LCA trunk is an independent risk factor for adverse prognosis.Conclusion. The use of second- and third-generation stents along with changes in the technical aspects of stenting of the unprotected LCA trunk leads to a substantial reduction in the risk of adverse cardiovascular events and allows the indications for intervention to be expanded in this patient category.
ISSN:0042-4676
2619-0478