Pruritus and Atopic Dermatitis: from Etiological Features to Management

Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was co...

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Main Authors: Nikolay N. Murashkin, Leonid A. Opryatin, Roman V. Epishev, Alexander I. Materikin, Eduard T. Ambarchian, Roman A. Ivanov, Dmitriy V. Fedorov, Daria S. Kukoleva
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2020-12-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/2508
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Summary:Pruritus is one of the main clinical manifestations of atopic dermatitis, and it significantly reduces the quality of life of patients in childhood. Scientific images on its pathophysiological basis have now undergone significant changes. The histamine exceptional role in pruritus development was confounded, as well as data on immune system involvement in its maintenance was given. This article presents current data on differential approaches to pruritus management depending on its etiopathogenetic characteristics. The role of dermocosmetics in restoration of the skin barrier as the first stage prevention of pruritus in atopic dermatitis was considered. The results of clinical studies showing efficacy of topical agents (innovative component with anti-pruritic action — STIMU-TEX) application are presented.
ISSN:1682-5527
1682-5535