Clinical Efficacy of Canrenone in Restoring Sinus Rhythm in Patients With Atrial Fibrillation—A Pilot, Randomized, Double-Blind Study

Clinical Efficacy of Canrenone in Restoring Sinus Rhythm in Patients With Atrial Fibrillation—A Pilot, Randomized, Double-Blind Study

Background and aims Renin-angiotensin-aldosterone system (RAAS) inhibition is an upstream therapy for managing atrial fibrillation (AF). Of all RAAS-inhibiting agents, only canrenone in the form of potassium canrenoate, a specific inhibitor of mineralocorticoid receptors, is administered intravenous...

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Main Authors: Rafał Dąbrowski MD, PhD, Agnieszka Segiet-Święcicka MD, PhD, Stefan Sawicki MD, PhD, Ilona Kowalik MD, PhD, Krzysztof Jaworski MD, PhD, Michał Farkowski MD, PhD, Agata Kubaszek-Kornatowska MD, PhD, Piotr Michałek MD, PhD, Mirosław Dłużniewski MD, PhD, Hanna Szwed MD, PhD, Tomasz Hryniewiecki MD, PhD, Jarosław Karwowski PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Journal of Cardiovascular Pharmacology and Therapeutics
Online Access:https://doi.org/10.1177/10742484251356361
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