BIOEQUIVALENCE STUDY OF GENERIC MOLNUPIRAVIR IN HEALTHY VOLUNTEERS

QR Code

BIOEQUIVALENCE STUDY OF GENERIC MOLNUPIRAVIR IN HEALTHY VOLUNTEERS

Molnupiravir is one of the drugs for the etiotropic therapy of a new coronavirus infection COVID-19. It has confirmed its clinical efficacy in the treatment of patients with mild and moderate COVID-19, including those who are at high risk of progressing to severe disease.The aim of the study was to...

Full description

Saved in:

Bibliographic Details
Main Authors:	V. B. Vasilyuk, A. Yu. Boroduleva, P. D. Sobolev, A. G. Nikiforova, V. G. Mozgovaya, O. V. Filon, A. V. Zinkovskaya, V. G. Ignatiev, M. Yu. Samsonov, I. S. Kozlova, E. K. Khanonina
Format:	Article
Language:	Russian
Published:	Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2023-02-01
Series:	Фармация и фармакология (Пятигорск)
Subjects:	covid-19 molnupiravir bioequivalence pharmacokinetics n-hydroxycytidine
Online Access:	https://www.pharmpharm.ru/jour/article/view/1221
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Bioequivalence study of generic nirmatrelvir in healthy volunteers
by: R. A. Oseshnyuk, et al.
Published: (2023-05-01)

Pharmacokinetics and bioequivalence of the generic and original dabigatran etexilate after a single dose in healthy volunteers
by: V. B. Vasilyuk, et al.
Published: (2024-10-01)

Simultaneous Determination of Major Molnupiravir Metabolite (β-D-N4-hydroxycytidine) and Favipiravir in Human Plasma by HPLC-MS/MS
by: T. N. Komarov, et al.
Published: (2023-02-01)

Phase I Pharmacokinetics Study of Oral Administration of Esperavir® (INN: Molnupiravir) (LLC "PROMOMED RUS", Russia)
by: T. N. Komarov, et al.
Published: (2024-03-01)

Reciprocal Impact of Molnupiravir and Favipiravir Monocomponents of the Combination Drug on Each Other's Pharmacokinetics in a Phase I Clinical Trial
by: T. N. Komarov, et al.
Published: (2024-03-01)

COMPARATIVE PHARMACOKINETICS AND EFFECT ON THE HEMODYNAMICS OF ORIGINAL AND GENERIC NEBIVOLOL IN HEALTHY VOLUNTEERS
by: E. I. Bambysheva, et al.
Published: (2016-05-01)

Pharmacokinetic and bioequivalence study of Telzap® Plus fixed-dose combination compared with MikardisPlus® in healthy volunteers after single administration
by: A. L. Khokhlov, et al.
Published: (2023-01-01)

Pharmacokinetics and Safety with Bioequivalence of Isosorbide Mononitrate Sustained-Release Tablets in Chinese Healthy Volunteers: Bioequivalence Study
by: Wu B, et al.
Published: (2025-07-01)

Single-Dose Bioequivalence Study of Rivaroxaban-Containing Medicinal Products in Healthy Volunteers
by: G. N. Gildeeva, et al.
Published: (2022-10-01)

Pharmacokinetic and bioequivalence study of Telzap® in comparison with Mikardis® in healthy subjects after single administrationl
by: A. L. Khokhlov, et al.
Published: (2023-01-01)

Study of the pharmacokinetic profile of the medicinal product Gidazepam®, tablets, 50 mg in a bioequivalence study
by: E. V. Baskakov, et al.
Published: (2023-11-01)

Bioequivalence study of tablet forms of risperidone, olanzapine and quetiapine in healthy volunteers
by: V. V. Pisarev, et al.
Published: (2013-04-01)

A COMPARATIVE ANALYSIS OF BIOEQUIVALENCE, CLINICAL EFFICACY AND SAFETY OF GENERIC VERSUS ORIGINAL CYCLOSPORINE AFTER KIDNEY TRANSPLANTATION
by: E. S. Stolyarevich, et al.
Published: (2015-04-01)

INFLUENCE OF SEX DIFFERENCES ON PHARMACOKINETICS OF DRUGS WITHIN THE FRAMEWORK OF BIOEQUIVALENCE STUDIES OF GENERIC MEDICINAL PRODUCTS
by: D. P. Romodanovsky, et al.
Published: (2018-09-01)

PLANNING AND EVALUATION OF BIOEQUIVALENCE STUDIES OF ATAZANAVIR PRODUCTS
by: N. E. Uvarova, et al.
Published: (2018-12-01)

Comparative Bioequivalence Studies of doxysam and doxycycline (Pfizer) by reversed phase HPLC.
by: Baghdad Science Journal
Published: (2010-03-01)

Bioequivalence of bisoprolol, coated tablets 10 mg JSC «Chimpharm» Republic of Kazakhstan
by: Y. M. Budach, et al.
Published: (2013-04-01)

Pharmacokinetic and Bioequivalence Study of the Two-component Drug Product "Ezetimibe + rosuvastatin" (JSC "Sanofi-aventis group", Russia): Resuts and Experience with the Use of Enzymatic Hydrolysis in the Analysis of Samples
by: A. L. Khokhlov, et al.
Published: (2023-02-01)

Pharmacokinetic and Bioequivalence Study of Telzap AM<sup>®</sup> (Telmisartan/amlodipine Fixed-dose Combination) and Coadministered Mikardis<sup>®</sup> (Telmisartan) and Norvask<sup>®</sup> (Amlodipine) in Healthy Subjects
by: V. Kubesh, et al.
Published: (2020-11-01)

Evaluation of Bioequivalence of Generic Imatinib Products and Generic Tacrolimus Products Based on Indirect Comparison of the Results of Their Bioequivalence Studies
by: D. V. Goryachev, et al.
Published: (2019-09-01)

Bioequivalence study of fixed-dose combination Losartan + amlodipine + rosuvastatin Sanofi in comparison with coadministered fixed- dose combination Lozap® AM and monocomponent drug Crestor® in healthy subjects
by: A. L. Khokhlov, et al.
Published: (2022-05-01)

Degree-Based and Neighborhood Degree Sum-Based Entropy Measures of Molnupiravir
by: Shibsankar Das, et al.
Published: (2025-06-01)

MOTIVATION AND PARTICIPATION EXPERIENCE OF HEALTHY VOLUNTEERS IN THE CLINICAL TRIALS OF BIOEQUIVALENCE IN RUSSIA
by: I. V. Mareev, et al.
Published: (2019-01-01)

Preclinical studies of antiviral activity of the RPH-137 fusion protein and molnupiravir against COVID-19
by: E. V. Shipaeva, et al.
Published: (2022-12-01)

Evaluation of bioequivalence of two tablet forms of lisinopril in healthy volunteers
by: S. A. Altynbekov, et al.
Published: (2013-09-01)

Molnupiravir and Nirmatrelvir/Ritonavir: The New Available Antiviral Options for COVID-19
by: Samuel Theodorus Sutanto, et al.
Published: (2023-01-01)

Comparative bioequivalence study of Pioglitazone tablets, 20 mg (JSC «Chimpharm», Kazakhstan) and Actos® Tablets, 30 mg («Eli Lilly Holdings, Takeda Global Research and Development Centre Europe Ltd»)
by: A. K. Sariev, et al.
Published: (2013-09-01)

METHODS OF STABILIZATION OF DRUG SUBSTANCES AND THEIR METABOLITES IN BIOLOGICAL FLUIDS DURING BIOANALYTICAL STUDY (REVIEW)
by: I. I. Yaichkov, et al.
Published: (2019-01-01)

Bioequivalence study of ondansetron tablets by HPLC-MS
by: E. S. Stepanova, et al.
Published: (2014-04-01)

Expert Approaches to the Assessment of Losartan Drugs Bioequivalence
by: D. P. Romodanovsky, et al.
Published: (2020-02-01)

Planning and Evaluation of Bioequivalence Studies of Telmisartan Generic Drug Products
by: A. L. Khokhlov, et al.
Published: (2019-09-01)

Real-world effectiveness and economic analysis of nirmatrelvir/ritonavir, remdesivir, and molnupiravir for treatment of COVID-19 among ambulatory patients in Thailand
by: Sirapat Korwiwattanakan, et al.
Published: (2025-08-01)

Planning Bioequivalence Studies in the Context of the COVID-19 Pandemic
by: D. P. Romodanovsky, et al.
Published: (2021-03-01)

A Comparative Parallel Study of Pharmacokinetics and Immunogenicity Following Single Intravenous Administration of Bevacizumab Biosimilar RPH-001 (Manufactured by R-Pharm Group, Russia) and Avastin® (Manufactured by F. Hoffmann-La Roche Ltd., Switzerland) in Healthy Male Volunteers
by: M. A. Kolganova, et al.
Published: (2019-09-01)

Highly variable medicines - specific aspects of bioequivalence studies
by: D. P. Romodanovsky, et al.
Published: (2018-02-01)

Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Analysis of Riluzole in Human Plasma and Its Application on a Bioequivalence Study
by: S. Mohammadzadeh, et al.
Published: (2023-02-01)

Russian development for drug independence in endocrinology: comparative analysis of bioequivalence, safety and tolerability of the first domestic liraglutide
by: A. S. Ametov, et al.
Published: (2023-11-01)

A comparative study of pharmacokinetics and bioequivalence of Cardiopril tablets 20 mg (JSC «Himfarm», Kazakhstan) and Monopril® tablets of 20 mg («Bristol-Myers Squibb SRL», Italy)
by: A. K. Sariev, et al.
Published: (2014-04-01)

Optimisation of Approaches to Adverse Event Analysis in Bioequivalence Clinical Trials
by: A. B. Verveda, et al.
Published: (2024-04-01)

Planning and evaluation of bioequivalence studies of rosuvastatin drug products
by: D. P. Romodanovsky, et al.
Published: (2018-02-01)