Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020

Pyogenic arthritis (PA) related mortality trends have not been studied well across various demographics in the United States (US). This cross-sectional study aimed to evaluate these trends among the US population aged ≥ 25 years from 1999–2020 using data from the CDC WONDER database. We identified a...

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Main Authors: Usama Qamar, Maaz Asif, Farhan Naeem, Eisha Mazhar
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-01-01
Series:Exploration of Musculoskeletal Diseases
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Online Access:https://www.explorationpub.com/uploads/Article/A100781/100781.pdf
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author Usama Qamar
Maaz Asif
Farhan Naeem
Eisha Mazhar
author_facet Usama Qamar
Maaz Asif
Farhan Naeem
Eisha Mazhar
author_sort Usama Qamar
collection DOAJ
description Pyogenic arthritis (PA) related mortality trends have not been studied well across various demographics in the United States (US). This cross-sectional study aimed to evaluate these trends among the US population aged ≥ 25 years from 1999–2020 using data from the CDC WONDER database. We identified all the deaths where PA was listed as the underlying or contributing cause of death, using the ICD-10 code M00. Age-adjusted mortality rates (AAMRs) were calculated per 1 million US population and the Joinpoint regression model was used to assess the annual mortality trends by calculating the annual percent change (APC) in AAMRs. Between 1999 and 2020, 13,965 total deaths occurred among US adults aged ≥ 25 years with an AAMR of 2.94. The overall AAMR of PA increased significantly from 1999 to 2020 with an APC of 2.01 (p < 0.01). Males and older adults had consistently higher AAMRs than their respective counterparts. Non-Hispanic (NH) American Indians/Alaska Natives and NH Blacks/African Americans had higher mortality rates compared with other racial groups. The Midwest had the highest overall AAMR, followed by the West, Northeast, and South regions. In conclusion, PA mortality has been on the rise and targeted interventions are warranted to reduce disproportionate mortality rates among vulnerable populations.
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spelling doaj-art-91d50b1c978044b0b29a6c0d9bc233fc2025-07-29T02:16:01ZengOpen Exploration Publishing Inc.Exploration of Musculoskeletal Diseases2836-64682025-01-01310078110.37349/emd.2025.100781Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020Usama Qamar0https://orcid.org/0009-0005-1727-6411Maaz Asif1Farhan Naeem2Eisha Mazhar3Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USADepartment of Medicine, King Edward Medical University, Lahore 54000, PakistanDepartment of Medicine, King Edward Medical University, Lahore 54000, PakistanDepartment of Medicine, Shifa College of Medicine, Islamabad 46000, PakistanPyogenic arthritis (PA) related mortality trends have not been studied well across various demographics in the United States (US). This cross-sectional study aimed to evaluate these trends among the US population aged ≥ 25 years from 1999–2020 using data from the CDC WONDER database. We identified all the deaths where PA was listed as the underlying or contributing cause of death, using the ICD-10 code M00. Age-adjusted mortality rates (AAMRs) were calculated per 1 million US population and the Joinpoint regression model was used to assess the annual mortality trends by calculating the annual percent change (APC) in AAMRs. Between 1999 and 2020, 13,965 total deaths occurred among US adults aged ≥ 25 years with an AAMR of 2.94. The overall AAMR of PA increased significantly from 1999 to 2020 with an APC of 2.01 (p < 0.01). Males and older adults had consistently higher AAMRs than their respective counterparts. Non-Hispanic (NH) American Indians/Alaska Natives and NH Blacks/African Americans had higher mortality rates compared with other racial groups. The Midwest had the highest overall AAMR, followed by the West, Northeast, and South regions. In conclusion, PA mortality has been on the rise and targeted interventions are warranted to reduce disproportionate mortality rates among vulnerable populations.https://www.explorationpub.com/uploads/Article/A100781/100781.pdfpyogenic arthritismortalitytrendsdisparities
spellingShingle Usama Qamar
Maaz Asif
Farhan Naeem
Eisha Mazhar
Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
Exploration of Musculoskeletal Diseases
pyogenic arthritis
mortality
trends
disparities
title Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
title_full Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
title_fullStr Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
title_full_unstemmed Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
title_short Patterns and inequities in pyogenic arthritis-related mortality in the United States from 1999–2020
title_sort patterns and inequities in pyogenic arthritis related mortality in the united states from 1999 2020
topic pyogenic arthritis
mortality
trends
disparities
url https://www.explorationpub.com/uploads/Article/A100781/100781.pdf
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AT eishamazhar patternsandinequitiesinpyogenicarthritisrelatedmortalityintheunitedstatesfrom19992020