Poly (D,L-lactide-co-glycolide) nanoparticles: Uptake by epithelial cells and cytotoxicity

Poly (D,L-lactide-co-glycolide) nanoparticles: Uptake by epithelial cells and cytotoxicity

Nanoparticles as drug delivery systems offer benefits such as protection of the encapsulated drug against degradation, site-specific targeting and prolonged blood circulation times. The aim of this study was to investigate nanoparticle uptake into Caco-2 cell monolayers, their co-localization within...

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Bibliographic Details
Main Authors: J. H. Hamman, L. A. Nkabinde, L. N. N. Shoba-Zikhali, B. Semete-Makokotlela, L. Kalombo, H. Swai, A. Grobler
Format: Article
Language:English
Published: Budapest University of Technology and Economics 2014-03-01
Series:eXPRESS Polymer Letters
Subjects:
Biocompatible polymers
PLGA nanoparticles
Cellular uptake
Caco-2 cells
Cytotoxicity
Online Access:http://www.expresspolymlett.com/letolt.php?file=EPL-0004774&mi=cd
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