Predicting Fetal Growth with Curve Fitting and Machine Learning

Monitoring fetal growth throughout pregnancy is essential for early detection of developmental abnormalities. This study developed a Taiwan-specific fetal growth reference using a web-based data collection platform and polynomial regression modeling. We analyzed ultrasound data from 980 pregnant wom...

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Bibliographic Details
Main Authors: Huan Zhang, Chuan-Sheng Hung, Chun-Hung Richard Lin, Hong-Ren Yu, You-Cheng Zheng, Cheng-Han Yu, Chih-Min Tsai, Ting-Hsin Huang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Bioengineering
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Online Access:https://www.mdpi.com/2306-5354/12/7/730
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Summary:Monitoring fetal growth throughout pregnancy is essential for early detection of developmental abnormalities. This study developed a Taiwan-specific fetal growth reference using a web-based data collection platform and polynomial regression modeling. We analyzed ultrasound data from 980 pregnant women, encompassing 8350 prenatal scans, to model six key fetal biometric parameters: abdominal circumference, crown–rump length, estimated fetal weight, head circumference, biparietal diameter, and femur length. Quadratic regression was selected based on a balance of performance and simplicity, with R<sup>2</sup> values exceeding 0.95 for most parameters. Confidence intervals and real-time anomaly detection were implemented through the platform. The results demonstrate the potential for efficient, population-specific fetal growth monitoring in clinical settings.
ISSN:2306-5354