Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine
Electrospinning has emerged as a versatile and cost-effective technique for fabricating nanofibers with a high surface area, tunable morphology, and exceptional mechanical properties, demonstrating significant potential for applications in biomedicine. This review summarizes the main parameters of t...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-06-01
|
| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/15/12/909 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839653196781322240 |
|---|---|
| author | Jingwen Liu Kai Wang Fengying Jin Jiayi Li Yile Bin Xiaofei Qian |
| author_facet | Jingwen Liu Kai Wang Fengying Jin Jiayi Li Yile Bin Xiaofei Qian |
| author_sort | Jingwen Liu |
| collection | DOAJ |
| description | Electrospinning has emerged as a versatile and cost-effective technique for fabricating nanofibers with a high surface area, tunable morphology, and exceptional mechanical properties, demonstrating significant potential for applications in biomedicine. This review summarizes the main parameters of the electrospinning process and fabrication methods of functionalized electrospun nanofibers (FENFs) through one-step functionalization and post-functionalization. The applications of FENFs, with their antibacterial activity, anti-inflammatory effects, and tissue regenerative effects, as well as their potential in drug delivery systems and sensors, showcase their capability to address challenges in wound healing, cancer therapy, and health monitoring. Current limitations and future research directions are also identified. This review provides valuable insights for advancing research on nanofiber-based materials and their practical implementations. |
| format | Article |
| id | doaj-art-8ff9a79adfba43a0ba33bf9a9df86bdb |
| institution | Matheson Library |
| issn | 2079-4991 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj-art-8ff9a79adfba43a0ba33bf9a9df86bdb2025-06-25T14:14:29ZengMDPI AGNanomaterials2079-49912025-06-01151290910.3390/nano15120909Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for BiomedicineJingwen Liu0Kai Wang1Fengying Jin2Jiayi Li3Yile Bin4Xiaofei Qian5The First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou 510515, ChinaSchool of Microelectronics, Fudan University, Shanghai 200433, ChinaElectrospinning has emerged as a versatile and cost-effective technique for fabricating nanofibers with a high surface area, tunable morphology, and exceptional mechanical properties, demonstrating significant potential for applications in biomedicine. This review summarizes the main parameters of the electrospinning process and fabrication methods of functionalized electrospun nanofibers (FENFs) through one-step functionalization and post-functionalization. The applications of FENFs, with their antibacterial activity, anti-inflammatory effects, and tissue regenerative effects, as well as their potential in drug delivery systems and sensors, showcase their capability to address challenges in wound healing, cancer therapy, and health monitoring. Current limitations and future research directions are also identified. This review provides valuable insights for advancing research on nanofiber-based materials and their practical implementations.https://www.mdpi.com/2079-4991/15/12/909electrospinningnanofibersbiomedicineantibacterialanti-inflammatorytissue engineering |
| spellingShingle | Jingwen Liu Kai Wang Fengying Jin Jiayi Li Yile Bin Xiaofei Qian Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine Nanomaterials electrospinning nanofibers biomedicine antibacterial anti-inflammatory tissue engineering |
| title | Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine |
| title_full | Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine |
| title_fullStr | Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine |
| title_full_unstemmed | Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine |
| title_short | Preparation Methods and Multifunctional Applications of Functionalized Electrospun Nanofibers for Biomedicine |
| title_sort | preparation methods and multifunctional applications of functionalized electrospun nanofibers for biomedicine |
| topic | electrospinning nanofibers biomedicine antibacterial anti-inflammatory tissue engineering |
| url | https://www.mdpi.com/2079-4991/15/12/909 |
| work_keys_str_mv | AT jingwenliu preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine AT kaiwang preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine AT fengyingjin preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine AT jiayili preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine AT yilebin preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine AT xiaofeiqian preparationmethodsandmultifunctionalapplicationsoffunctionalizedelectrospunnanofibersforbiomedicine |