Reaction of neurons of internal layers of the retina to combined influence of ionizing radiation and light

The purpose of the presented work was the establishment of a character of modifying influence of ionizing radiation on damages of neurons of internal nuclear and ganglionic layers of a retina caused by light. The investigation revealed that changes of neurons of the internal nuclear and ganglionic l...

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Bibliographic Details
Main Authors: A. V. Potapov, M. V. Svetlik
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2006-06-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/3071
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Summary:The purpose of the presented work was the establishment of a character of modifying influence of ionizing radiation on damages of neurons of internal nuclear and ganglionic layers of a retina caused by light. The investigation revealed that changes of neurons of the internal nuclear and ganglionic layers after X-ray, light (200 lk, the 1st, 2nd, 7th, 14th, 30th days) and combined influence have similar nature, but differ in a degree of expression and manifest by reactive and destructive changes of organelles. Associated neurons showed relative resistance to investigated influences in comparison with multi-polar neurons of ganglionic layer. Combined ionizing radiation and light cause substantial growth of number of hyper-chrome and picnotic multi-polar neurons of ganglionic layer of a retina. Synergic effect is mostly expressed on 7-th-14-th day of the experiment and results in progressing growth of the number of hyper chrome multi-polar neurons.
ISSN:1682-0363
1819-3684