Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study
Introduction: Colorectal cancer is a major global health concern with variable incidence and presentation across regions. The study was aimed to describe the clinic-epidemiological profile of colorectal cancer in a tertiary care hospital in Nepal. Methods: This observational cross-section study was...
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Nepal Medical Association
2025-07-01
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| Series: | Journal of Nepal Medical Association |
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| Online Access: | https://www.jnma.com.np/jnma/index.php/jnma/article/view/9157 |
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| author | Rita Kumari Mahaseth Rashika Upadhyaya Prakash Chandra Panjiyar Neha Jha Ujjwal Kumar Jha |
| author_facet | Rita Kumari Mahaseth Rashika Upadhyaya Prakash Chandra Panjiyar Neha Jha Ujjwal Kumar Jha |
| author_sort | Rita Kumari Mahaseth |
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Introduction: Colorectal cancer is a major global health concern with variable incidence and presentation across regions. The study was aimed to describe the clinic-epidemiological profile of colorectal cancer in a tertiary care hospital in Nepal.
Methods: This observational cross-section study was conducted at a tertiary care hospital in Nepal from April 2021 to March 2024. Ethical clearance was obtained (Reference number: IRC/NMCTH/024/21). A total sampling method was used to include 69 patients with histologically confirmed colorectal cancer. Data were collected from patient records and analyzed using Statistical Package for the Social Sciences version 16.0. Point estimate at 95%Confidence Interval was calculated along with frequency and percentages
for binary data, and mean and standard deviation for continuous data.
Results: Out of 69 patients, 39 (56.52%) were male and 30 (43.48%) female. The most affected age group was 35–50 years, accounting for 26 (37.68%) patients. Rectum including recto-sigmoid colon was the most common tumor location in 38 (55.07%) cases. The most common presenting symptom was bowel habit change, seen in 46 (66.67%) patients. Lower anterior resection was performed in 26 (37.68%) cases. Histologically, moderately differentiated adenocarcinoma was the predominant type, found in 53 (76.81%) patients.
Conclusions: Colorectal cancer in this study predominantly affected middle- aged males, with the rectum being the common site and moderately differentiated adenocarcinoma the main histological type.
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| format | Article |
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| issn | 0028-2715 1815-672X |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nepal Medical Association |
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| series | Journal of Nepal Medical Association |
| spelling | doaj-art-8e4d2f4b09a94a07946a36f3cfb1b50b2025-08-03T10:21:15ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2025-07-016328810.31729/jnma.9157Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational StudyRita Kumari Mahaseth0Rashika Upadhyaya1Prakash Chandra Panjiyar2Neha Jha 3Ujjwal Kumar Jha4Oncology Unit, Nepal Medical College and Teaching Hospital, Attarkhel, Kathmandu, NepalTribhuvan University Teaching Hospital: Kathmandu, Bagmati Province, NepalNepalese Army Institute of Health Services: Kathmandu, Bagmati Province, NepalNepal Medical College Teaching Hospital: Kathmandu, Bagmati Province, NepalPatan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal Introduction: Colorectal cancer is a major global health concern with variable incidence and presentation across regions. The study was aimed to describe the clinic-epidemiological profile of colorectal cancer in a tertiary care hospital in Nepal. Methods: This observational cross-section study was conducted at a tertiary care hospital in Nepal from April 2021 to March 2024. Ethical clearance was obtained (Reference number: IRC/NMCTH/024/21). A total sampling method was used to include 69 patients with histologically confirmed colorectal cancer. Data were collected from patient records and analyzed using Statistical Package for the Social Sciences version 16.0. Point estimate at 95%Confidence Interval was calculated along with frequency and percentages for binary data, and mean and standard deviation for continuous data. Results: Out of 69 patients, 39 (56.52%) were male and 30 (43.48%) female. The most affected age group was 35–50 years, accounting for 26 (37.68%) patients. Rectum including recto-sigmoid colon was the most common tumor location in 38 (55.07%) cases. The most common presenting symptom was bowel habit change, seen in 46 (66.67%) patients. Lower anterior resection was performed in 26 (37.68%) cases. Histologically, moderately differentiated adenocarcinoma was the predominant type, found in 53 (76.81%) patients. Conclusions: Colorectal cancer in this study predominantly affected middle- aged males, with the rectum being the common site and moderately differentiated adenocarcinoma the main histological type. https://www.jnma.com.np/jnma/index.php/jnma/article/view/9157clinico-epidemiological profilecolorectal cancertertiary centre hospital |
| spellingShingle | Rita Kumari Mahaseth Rashika Upadhyaya Prakash Chandra Panjiyar Neha Jha Ujjwal Kumar Jha Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study Journal of Nepal Medical Association clinico-epidemiological profile colorectal cancer tertiary centre hospital |
| title | Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study |
| title_full | Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study |
| title_fullStr | Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study |
| title_full_unstemmed | Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study |
| title_short | Clinico-epidemiological Profile of Colorectal Cancer in Oncology Department of Tertiary Centre Hospital in Nepal: An Observational Study |
| title_sort | clinico epidemiological profile of colorectal cancer in oncology department of tertiary centre hospital in nepal an observational study |
| topic | clinico-epidemiological profile colorectal cancer tertiary centre hospital |
| url | https://www.jnma.com.np/jnma/index.php/jnma/article/view/9157 |
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