Series 2: Development of a Multiplex Amplicon Next Generation Sequencing Assay for Rapid Assessment of Resistance-Associated Mutations in <i>M. tuberculosis</i> Clinical Cases

Series 2: Development of a Multiplex Amplicon Next Generation Sequencing Assay for Rapid Assessment of Resistance-Associated Mutations in <i>M. tuberculosis</i> Clinical Cases

Treatment of <i>Mycobacterium tuberculosis</i> requires multi-drug regimens, and resistance to any individual antibiotic can compromise outcomes. For slow-growing organisms like <i>M. tuberculosis</i>, rapid detection of resistance-conferring mutations enables timely initiati...

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Bibliographic Details
Main Authors: Adriana Cabrera, Tracy Lee, Kathleen Kolehmainen, Trevor Hird, Danielle Jorgensen, Calvin Ka-Fung Lo, Hasan Hamze, Alan O’Dwyer, Dan Fornika, Rupinder Kaur KhunKhun, Mabel Rodrigues, Natalie Prystajecky, John Tyson, James E. A. Zlosnik, Inna Sekirov
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Tropical Medicine and Infectious Disease
Subjects:
tuberculosis
antibiotic resistance
next generation sequencing
molecular
Online Access:https://www.mdpi.com/2414-6366/10/7/194
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