Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vascular complications

Objective(s): Increased nuclear factor (NF-kβ) and carbonyl stress due to decreased glyoxalase-1 activity (Glo-I) contribute significantly to insulin resistance and vascular complications. Therefore, we aimed to study the impact of the combination of thiamine and niacin on hepatic NF-kβ signaling, m...

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Bibliographic Details
Main Authors: Sina Mahdavifard, Hamid Reza Malekzadeh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-01-01
Series:Iranian Journal of Basic Medical Sciences
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Online Access:https://ijbms.mums.ac.ir/article_24945_a8c72d0a3b45844e70934de7b291b2b3.pdf
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