Trend in the use of biological drugs in pediatric patients with immune-mediated inflammatory diseases: Insight from the large-scale Italian VALORE project

Trend in the use of biological drugs in pediatric patients with immune-mediated inflammatory diseases: Insight from the large-scale Italian VALORE project

Real-world data on biological drug use in pediatric patients with immune-mediated inflammatory diseases (IMIDs) are scarce. This retrospective, population-based, cohort study aimed to provide an overview of biological drug use among children and adolescents with IMIDs from 2010 to 2023 using the Ita...

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Main Authors: Chiara Bellitto, Ylenia Ingrasciotta, Federica Soardo, Andrea Spini, Luca L’Abbate, Giorgia Pellegrini, Clément Mathieu, Massimo Carollo, Marco Tuccori, Olivia Leoni, Arianna Mazzone, Domenica Ancona, Paolo Stella, Anna Cavazzana, Angela Scapin, Sara Lopes, Valeria Belleudi, Stefano Ledda, Paolo Carta, Paola Rossi, Lucian Ejlli, Ester Sapigni, Aurora Puccini, Rita Francesca Scarpelli, Giovambattista De Sarro, Rosa Gini, Alessandra Allotta, Sebastiano Addario Pollina, Giampaolo Bucaneve, Antea Maria Pia Mangano, Francesco Balducci, Carla Sorrentino, Ilenia Senesi, Ugo Trama, Francesca Futura Bernardi, Roberto Da Cas, Giorgio Costa, Silvana Anna Maria Urru, Annalisa Campomori, Stefania Spila Alegiani, Marco Massari, Romina Gallizzi, Gianluca Trifirò
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Pharmacological Research
Subjects:
Drug utilization
Pediatrics
Pharmacoepidemiology
Immune-mediated inflammatory diseases
Biological drugs
Persistence
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825002683
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