Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging
The incidence and prevalence of amyloid cardiomyopathy (AC) has been increasing in recent years, and this diagnosis is often detected at the final stage. This determines late prescription of specific therapy and worsening prognosis of patients. Unfortunately, doctors are not sufficiently informed ab...
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| Format: | Article |
| Language: | Russian |
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InterMedservice
2024-11-01
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| Series: | Евразийский Кардиологический Журнал |
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| Online Access: | https://www.heartj.asia/jour/article/view/6489 |
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| author | M. V. Ezhikova S. N. Nasonova D. V. Ustyuzhanin M. A. Shariya I. V. Zhirov S. N. Tereshchenko |
| author_facet | M. V. Ezhikova S. N. Nasonova D. V. Ustyuzhanin M. A. Shariya I. V. Zhirov S. N. Tereshchenko |
| author_sort | M. V. Ezhikova |
| collection | DOAJ |
| description | The incidence and prevalence of amyloid cardiomyopathy (AC) has been increasing in recent years, and this diagnosis is often detected at the final stage. This determines late prescription of specific therapy and worsening prognosis of patients. Unfortunately, doctors are not sufficiently informed about the pathogenesis of AC and diagnostic methods. This circumstance leads to prolongation of time from the manifestation of the disease to the diagnosis. Despite the presence of a large number of AC masks, a number of specific clinical diagnostic markers called «red flags» helps to suspect AC. In addition, the development of diagnostic algorithms using non-invasive imaging methods can help not only in diagnosing AC at an early stage of the disease, but also in determining the type of amyloidosis, that determines the success of timely administration of disease-modifying therapy. The aim of this review is to analyze the possibility of using MRI criteria to attempt non-invasive typing of amyloidosis and to differentiate ATTR and AL AС. |
| format | Article |
| id | doaj-art-8db4d2ee7eb24a9fa918ae2f22fc739c |
| institution | Matheson Library |
| issn | 2225-1685 2305-0748 |
| language | Russian |
| publishDate | 2024-11-01 |
| publisher | InterMedservice |
| record_format | Article |
| series | Евразийский Кардиологический Журнал |
| spelling | doaj-art-8db4d2ee7eb24a9fa918ae2f22fc739c2025-08-03T13:28:57ZrusInterMedserviceЕвразийский Кардиологический Журнал2225-16852305-07482024-11-0104909710.38109/2225-1685-2024-4-91-976364Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imagingM. V. Ezhikova0S. N. Nasonova1D. V. Ustyuzhanin2M. A. Shariya3I. V. Zhirov4S. N. Tereshchenko5E.I. Chazov National Medical Research Center of Cardiology; A.L. Myasnikov institute of clinical cardiologyE.I. Chazov National Medical Research Center of Cardiology; A.L. Myasnikov institute of clinical cardiologyE.I. Chazov National Medical Research Center of Cardiology; A.L. Myasnikov institute of clinical cardiologyE.I. Chazov National Medical Research Center of Cardiology; A.L. Myasnikov institute of clinical cardiologyE.I. Chazov National Medical Research Center of Cardiology; A.L. Myasnikov institute of clinical cardiology; Russian Medical Academy of Continuous Professional EducationE.I. Chazov National Medical Research Center of CardiologyThe incidence and prevalence of amyloid cardiomyopathy (AC) has been increasing in recent years, and this diagnosis is often detected at the final stage. This determines late prescription of specific therapy and worsening prognosis of patients. Unfortunately, doctors are not sufficiently informed about the pathogenesis of AC and diagnostic methods. This circumstance leads to prolongation of time from the manifestation of the disease to the diagnosis. Despite the presence of a large number of AC masks, a number of specific clinical diagnostic markers called «red flags» helps to suspect AC. In addition, the development of diagnostic algorithms using non-invasive imaging methods can help not only in diagnosing AC at an early stage of the disease, but also in determining the type of amyloidosis, that determines the success of timely administration of disease-modifying therapy. The aim of this review is to analyze the possibility of using MRI criteria to attempt non-invasive typing of amyloidosis and to differentiate ATTR and AL AС.https://www.heartj.asia/jour/article/view/6489transthyretin amyloid cardiomyopathymagnetic resonance imaginglate gadolinium enhancementmyocardial mappingextracellular volume fraction |
| spellingShingle | M. V. Ezhikova S. N. Nasonova D. V. Ustyuzhanin M. A. Shariya I. V. Zhirov S. N. Tereshchenko Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging Евразийский Кардиологический Журнал transthyretin amyloid cardiomyopathy magnetic resonance imaging late gadolinium enhancement myocardial mapping extracellular volume fraction |
| title | Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging |
| title_full | Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging |
| title_fullStr | Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging |
| title_full_unstemmed | Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging |
| title_short | Amyloid cardiomyopathy: сlinical significance and diagnostic value of magnetic resonance imaging |
| title_sort | amyloid cardiomyopathy сlinical significance and diagnostic value of magnetic resonance imaging |
| topic | transthyretin amyloid cardiomyopathy magnetic resonance imaging late gadolinium enhancement myocardial mapping extracellular volume fraction |
| url | https://www.heartj.asia/jour/article/view/6489 |
| work_keys_str_mv | AT mvezhikova amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging AT snnasonova amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging AT dvustyuzhanin amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging AT mashariya amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging AT ivzhirov amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging AT sntereshchenko amyloidcardiomyopathyslinicalsignificanceanddiagnosticvalueofmagneticresonanceimaging |