ENDOTOXINEMIA AND ATHEROSCLEROSIS

The background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atheroscler...

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Main Authors: Y. S. Schwarz, M. I. Dushkin
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2001-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2116
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author Y. S. Schwarz
M. I. Dushkin
author_facet Y. S. Schwarz
M. I. Dushkin
author_sort Y. S. Schwarz
collection DOAJ
description The background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atherosclerosis and Gram-negative infections, plasma and cellular targets and proatherogenic effects of endotoxin. Suggestion on the possible role of LPS-lipoprotein complexes is proposed and detaily discussed. Literature data on the endotoxin effects upon lipoprotein metabolism and foam cell formation are presented.
format Article
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institution Matheson Library
issn 1560-4071
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language Russian
publishDate 2001-08-01
publisher «FIRMA «SILICEA» LLC
record_format Article
series Российский кардиологический журнал
spelling doaj-art-8da80039d6b1400d834b3fa1097c037f2025-08-04T12:59:56Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202001-08-010483921869ENDOTOXINEMIA AND ATHEROSCLEROSISY. S. Schwarz0M. I. Dushkin1НИИТ СО РАМН, НИИКИ СО РАМН, НовосибирскНИИТ СО РАМН, НИИКИ СО РАМН, НовосибирскThe background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atherosclerosis and Gram-negative infections, plasma and cellular targets and proatherogenic effects of endotoxin. Suggestion on the possible role of LPS-lipoprotein complexes is proposed and detaily discussed. Literature data on the endotoxin effects upon lipoprotein metabolism and foam cell formation are presented.https://russjcardiol.elpub.ru/jour/article/view/2116atherosclerosisendotoxinbacterial lipopolysaccharides
spellingShingle Y. S. Schwarz
M. I. Dushkin
ENDOTOXINEMIA AND ATHEROSCLEROSIS
Российский кардиологический журнал
atherosclerosis
endotoxin
bacterial lipopolysaccharides
title ENDOTOXINEMIA AND ATHEROSCLEROSIS
title_full ENDOTOXINEMIA AND ATHEROSCLEROSIS
title_fullStr ENDOTOXINEMIA AND ATHEROSCLEROSIS
title_full_unstemmed ENDOTOXINEMIA AND ATHEROSCLEROSIS
title_short ENDOTOXINEMIA AND ATHEROSCLEROSIS
title_sort endotoxinemia and atherosclerosis
topic atherosclerosis
endotoxin
bacterial lipopolysaccharides
url https://russjcardiol.elpub.ru/jour/article/view/2116
work_keys_str_mv AT ysschwarz endotoxinemiaandatherosclerosis
AT midushkin endotoxinemiaandatherosclerosis