ENDOTOXINEMIA AND ATHEROSCLEROSIS
The background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atheroscler...
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Format: | Article |
Language: | Russian |
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«FIRMA «SILICEA» LLC
2001-08-01
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Series: | Российский кардиологический журнал |
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2116 |
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author | Y. S. Schwarz M. I. Dushkin |
author_facet | Y. S. Schwarz M. I. Dushkin |
author_sort | Y. S. Schwarz |
collection | DOAJ |
description | The background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atherosclerosis and Gram-negative infections, plasma and cellular targets and proatherogenic effects of endotoxin. Suggestion on the possible role of LPS-lipoprotein complexes is proposed and detaily discussed. Literature data on the endotoxin effects upon lipoprotein metabolism and foam cell formation are presented. |
format | Article |
id | doaj-art-8da80039d6b1400d834b3fa1097c037f |
institution | Matheson Library |
issn | 1560-4071 2618-7620 |
language | Russian |
publishDate | 2001-08-01 |
publisher | «FIRMA «SILICEA» LLC |
record_format | Article |
series | Российский кардиологический журнал |
spelling | doaj-art-8da80039d6b1400d834b3fa1097c037f2025-08-04T12:59:56Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202001-08-010483921869ENDOTOXINEMIA AND ATHEROSCLEROSISY. S. Schwarz0M. I. Dushkin1НИИТ СО РАМН, НИИКИ СО РАМН, НовосибирскНИИТ СО РАМН, НИИКИ СО РАМН, НовосибирскThe background of the hypothesis of the involvement of bacterial lipopolysaccharides in initiation and development of atherosclerosis is presented. Special accent is done on the incidence of endotoxinemia, the time of persistence of bioactive endotoxin in the tissues, association between atherosclerosis and Gram-negative infections, plasma and cellular targets and proatherogenic effects of endotoxin. Suggestion on the possible role of LPS-lipoprotein complexes is proposed and detaily discussed. Literature data on the endotoxin effects upon lipoprotein metabolism and foam cell formation are presented.https://russjcardiol.elpub.ru/jour/article/view/2116atherosclerosisendotoxinbacterial lipopolysaccharides |
spellingShingle | Y. S. Schwarz M. I. Dushkin ENDOTOXINEMIA AND ATHEROSCLEROSIS Российский кардиологический журнал atherosclerosis endotoxin bacterial lipopolysaccharides |
title | ENDOTOXINEMIA AND ATHEROSCLEROSIS |
title_full | ENDOTOXINEMIA AND ATHEROSCLEROSIS |
title_fullStr | ENDOTOXINEMIA AND ATHEROSCLEROSIS |
title_full_unstemmed | ENDOTOXINEMIA AND ATHEROSCLEROSIS |
title_short | ENDOTOXINEMIA AND ATHEROSCLEROSIS |
title_sort | endotoxinemia and atherosclerosis |
topic | atherosclerosis endotoxin bacterial lipopolysaccharides |
url | https://russjcardiol.elpub.ru/jour/article/view/2116 |
work_keys_str_mv | AT ysschwarz endotoxinemiaandatherosclerosis AT midushkin endotoxinemiaandatherosclerosis |